49ers vs Panthers Prediction, Odds, Picks, Best Bets for NFL Week 12 Monday Night Football

In NFL action on Monday, the San Francisco 49ers take on the Carolina Panthers.

All the info you need is below, in order to make a smart wager on this matchup at FanDuel Sportsbook.

49ers vs Panthers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (69.2%)

49ers vs Panthers Point Spread

The 49ers are 7.5-point favorites against the Panthers. The 49ers are -102 to cover the spread, while the Panthers are -120 to cover as a 7.5-point underdog.

49ers vs Panthers Over/Under

The 49ers-Panthers game on Nov. 24 has been given an over/under of 49.5 points. The over is -110 and the under is -110.

49ers vs Panthers Moneyline

San Francisco is a -405 favorite on the moneyline, while Carolina is a +320 underdog on the road.

49ers vs Panthers Betting Trends

• San Francisco's record against the spread is 6-5-0.
• Out of 11 49ers games so far this season, seven have hit the over.
• The Panthers have seven wins in 11 contests against the spread this year.
• As a 7.5-point underdog or greater, Carolina has one win ATS (1-1) this year.
• Out of 11 Panthers games so far this year, six have hit the over.

Check out even more in-depth 49ers vs. Panthers analysis on FanDuel Research.

49ers vs Panthers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-405) | CAR: (+320)
• Spread: SF: -7.5 (-102) | CAR: +7.5 (-120)
• Total: 49.5 -- Over: (-110) | Under: (-110)

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