Vanderbilt vs Alabama Prediction, Odds & Betting Trends for College Football Game on FanDuel Sportsbook

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Vanderbilt vs Alabama prediction, odds and betting trends for NCAA college football game.
Vanderbilt vs Alabama prediction, odds and betting trends for NCAA college football game. / Associated Press
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Vanderbilt vs Alabama Week 4 Game Info

2022 NCAA College Football Game
Vanderbilt Commodores (3-1, 0-0 SEC) vs. Alabama Crimson Tide (3-0, 0-0 SEC)
Date: Saturday, Sept. 24, 2022
Time: 7:30 p.m. ET
Venue: Bryant-Denny Stadium — Tuscaloosa, AL
Coverage: SEC Network

Week 4 of the 2022 NCAA college football season includes an SEC matchup between the Vanderbilt Commodores and No. 2 Alabama Crimson Tide.

It's the conference opener for both teams and their first meeting since 2017 when Alabama crushed Vanderbilt, 59-0.

Vanderbilt vs Alabama Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: VAN: (NL) | ALA: (NL)
Spread: VAN: +40.5 (-110) | ALA: -40.5 (-110)
Total: 58.5 — Over: (-110) | Under: (-110)

Alabama is a huge favorite of -40.5 points, and there is no moneyline due to the large spread. The Saturday night game also features an above-average total of 58.5 points.

Vanderbilt vs Alabama Prediction & Pick


Vanderbilt is projected as the worst team in the SEC, but the Commodores' offense has played well and scored more than expected through four games. Vandy has scored 63, 42, 25 and 38 points while winning three times.

Freshman quarterback A.J. Swann earned his first career start for Vandy last week and made the most of it. He earned SEC Freshman of the Week honors after passing for 255 yards and 4 TDs in a 38-28 win over Northern Illinois.

The passing game has been much more efficient than expected, and the Commodores' offensive line is doing a great job of keeping defenses out of the backfield. Vanderbilt hopes to get RB Rocko Griffin back, but he remains questionable vs Alabama and has not played since the opening win over Hawaii.

Alabama crushed UL Monroe last week, 63-7, after the close call vs Texas. Vanderbilt's power rating is more than 10 points higher than ULM's, however, and 'Bama was laying -49.5 to ULM. The Commodores can move the ball better, but scoring will still be tough against the Crimson Tide's defense. A blowout seems likely with Vanderbilt unable to slow Alabama with its top-rated QB Bryce Young, skill players and offensive line. Accordingly, betting the Over on the total is the preferred play.

Final Score Prediction: Alabama: 49 | Vanderbilt: 16

Vanderbilt vs Alabama Betting Trends

  • Vanderbilt has lost 21 straight SEC games, and is 0-10 in their last 10 games vs Alabama.
  • Vanderbilt is 6-2 against the spread (ATS) in their last 8 games.
  • The total has gone Over in all four Vanderbilt games this season.
  • Alabama is 10-0 SU in their last 10 home games.
  • The total has gone Under in 6 of Alabama's last 7 games against Vanderbilt.

Vanderbilt vs Alabama Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

All four of Vanderbilt's games have gone over the total. Alabama's defense is dominant, but the Crimson Tide have only forced one takeaway this season. Alabama also had a whopping 15 penalties during its narrow 20-19 escape at Texas--a record under Nick Saban. Clearly this is a mismatch, but the huge spread is the equalizer.

Vanderbilt has already exceeded their season win totals from the past two years combined, and the offense is much better than projected. The average margin over the posted total in Vandy games is 13 points per game, so we should feel pretty safe taking the Over here.

Bet: Over 58.5 (-110)

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