Twins vs Guardians Prediction, Odds & Best Bet for May 5 (Bailey Ober Leads Minnesota to Another Strong Showing)

Minnesota Twins vs Cleveland Guardians prediction, odds and betting insights for MLB regular season game.
Minnesota Twins vs Cleveland Guardians prediction, odds and betting insights for MLB regular season game. / AP Photo/Craig Lassig

The Cleveland Guardians (14-17) will try to put their funk behind them when they host the Minnesota Twins (18-14) at Progressive Field on Friday, May 5.

Twins vs Guardians Game Info

  • Date: Friday, May 5, 2023
  • Time: 7:10 p.m. ET
  • Venue: Progressive Field -- Cleveland, Ohio
  • Coverage: Apple TV+

The Guardians were in a marathon less than 24 hours ago, picking up a 7-3 victory over the Chicago White Sox in a 12-inning affair. Meanwhile, the Guardians went head-to-head with the Yankees yesterday, only to lose 4-3 after 10 innings — the former's 11th loss in their last 16 games.

Twins vs Guardians Odds & Spread

  • All MLB betting lines, odds and prop bets are from FanDuel Sportsbook.
  • Moneyline: MIN: (-126) | CLE: (+108)
  • Spread: MIN: -1.5 (+134) | CLE: +1.5 (-162)
  • Total: 8.5 -- Over: (-112) | Under: (-108)

The Twins enter this contest as road favorites on the moneyline and spread per FanDuel Sportsbook's odds. This 7:10 p.m. ET clash also features an over/under of 8.5 runs with the Over being favored at -112 odds.

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Twins vs Guardians Betting Trends

  • Minnesota is 10-4 straight up in its last 14 games against the AL Central.
  • Cleveland is 6-1 straight up in its last seven home games against Minnesota.
  • The total has hit the over in five of Minnesota's last six road games.
  • The total has hit the under in four of Cleveland's last six games against Minnesota.

Twins vs Guardians Prediction & Pick

The Twins are sending Bailey Ober to the mound for tonight's start. The 27-year-old righty has been solid in his limited work this season, going 1-0 with a 1.59 ERA while allowing just 5.6 hits per nine innings in two starts. It's a small sample size, though, so it'll be interesting to see if he keeps the ball rolling.

On the other side, Cleveland starter Peyton Battenfield is searching for his first MLB win. The former Oklahoma State product is 0-2 through four appearances (three starts), pitching to a 4.67 ERA while allowing 1.6 home runs and 5.7 walks per 9 IP. He looked awful in his last showing, giving up three runs on as many hits with four walks over just two innings.

The Guardians are playing uninspiring baseball lately and the fact that they're just 4-8 at home can't be ignored. With the Twins also having the pitching advantage due to Ober's solid play, I see them winning for the second time in as many nights.

Final Score Prediction: Twins: 5 | Guardians: 2

Twins vs Guardians Best Bet

As for the game's best bet, I'm going with the Twins outright on the moneyline. There's decent value at -126 on the moneyline and I just can't see them losing to the Guardians, who are 5-11 in their previous 16 outings. Taking Cleveland's home struggles into account, this is clearly Minnesota's game to lose.

Bet: Twins to Win Outright (-126)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.