Titans vs Chargers Prediction, Odds & Best Bets for Week 15 (Justin Herbert Torches Tennessee's Defense)

Titans vs Chargers Week 15 Game Info

2022 NFL Regular Season — Week 15
Tennessee Titans (7-6, 4-3 Away) vs. Los Angeles Chargers (7-6, 3-3 Home)
Date: Sunday, Dec. 18, 2022
Time: 4:25 p.m. ET
Venue: SoFi Stadium — Inglewood, CA
Coverage: CBS

Two teams fighting for playoff positioning meet head-to-head in Week 15 as the Tennessee Titans visit the Los Angeles Chargers. The Titans saw their losing streak reach three games thanks to a 36-22 loss to the Jacksonville Jaguars on Sunday. Derrick Henry was responsible for two costly fumbles.

Meanwhile, the Chargers earned one of their best wins of the season in a 23-17 victory over the Miami Dolphins in Week 14. Quarterback Justin Herbert balled out with 367 passing yards and 1 touchdown. Mike Williams was on the receiving end of that score and logged 116 yards on 6 catches.

Titans vs Chargers Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: TEN: (+130) | LAC: (-152)
Spread: TEN: +3 (-118) | LAC: -3 (-104)
Total: 47.5 — Over: (-105) | Under: (-115)

The Chargers enter this contest as small home favorites on the moneyline and spread on FanDuel Sportsbook's odds. This 4:25 p.m. ET clash also features one of the higher totals on the Week 15 slate at 47.5 points.

Titans vs Chargers Prediction & Pick

The Titans enter this game in a world of hurt. Three straight losses have put a damper on what was a great start to the 2022 season. Tennessee has scored an average of 16.0 points during that span, while allowing an average of 30.3 points (No. 29 in NFL). The defense continues to get dominated.

Head coach Mike Vrabel's team has allowed a whopping 754 passing yards over the last two weeks and now faces one of the best passing offenses in the league. The Chargers have posted a passing play percentage of 66.8% (No. 2 in NFL) and average a 272.9 passing yards per game (No. 3 in NFL).

The Chargers are also 11-2 straight up in their last 13 games against the Titans, so I'll back the home team with confidence.

Final Score Prediction: Titans: 21 | Chargers: 30

Titans vs Chargers Betting Trends

- Tennessee is 5-1 against the spread (ATS) in its last six away games.
- The total has hit the under in seven of Tennessee's last 10 games.
- The Chargers are 11-2 straight up in their last 13 games against Tennessee.
- The total has hit the over in seven of the Charger's last 10 home games.

Titans vs Chargers Best Bet

Not only are the Chargers 8-2 straight up in their last 10 games against the Titans, but they are also 7-2-1 against the spread (ATS) during that stretch. This is the first time Tennessee's defense has ever seen Herbert, too. Dealing with his insane arm strength and elite ball placement is going to be tough.

Tennessee has posted the fifth-worst pass defense DVOA rating and its average scoring margin on the road sits at -4.9. It's not hard to tell that the Chargers are in the perfect position to pull away in the second half of this game behind their air attack. This team is healthy and ready to make a statement.

Bet: Los Angeles Chargers -3 (-104)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.