Tennessee vs Pittsburgh Prediction, Odds, & Betting Trends for College Football Week 2 Game

Tennessee vs Pittsburgh Week 2 Game Info

2022 NCAA College Football Game
Tennessee Volunteers (1-1, 0-0) vs. Pitt Panthers (1-0, 0-0)
Date: Saturday, Sept. 10, 2022
Time: 3:30 p.m. ET
Venue: Acrisure Stadium — Pittsburgh, PA
Coverage: ABC

College football's Week 2 Saturday schedule includes the No. 24 Tennessee Volunteers taking on the No. 17 Pittsburgh Panthers at Acrisure Stadium in Steel City. It's the second edition of the Johnny Majors Classic and will be televised on ABC at 3:30 p.m. ET.

Tennessee vs Pittsburgh Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: TENN: (-250) | PITT: (+202)
Spread: TENN: -6.5 (-114) | PITT: +6.5 (-106)
Total: 66.5 — Over: (-110) | Under: (-110)

Tennessee enters as the road favorite despite a lower top-25 ranking. The Volunteers are -6.5 on the spread and -250 on the moneyline. National TV coverage at ABC at 3:30 p.m. ET and the game total is 66.5; well above the college football average total of 57 points.

Tennessee vs Pittsburgh Prediction & Pick

A good match-up for Tennessee, who plays with redemption following last year's early season loss to Pitt, 41-34. The oddsmakers are not fooled by the rankings or Pitt's win last week. Tennessee can stretch the field against Pitt's press coverage and senior QB Hendon Hooker will have success through the air. Tennessee can balance the attack after rushing 51 times for 218 yards last week. Pitt allowed 190 rushing yards to West Virginia, and the Vols figure to control the trenches and make more big plays in victory.

Final Score Prediction: Tennessee: 37 | Pittsburgh 24

Tennessee vs Pittsburgh Betting Trends

• Tennessee is 0-3 straight up (SU) and against the spread (ATS) against Pittsburgh.
• Tennessee is 1-4 SU in their last five true road openers.
• Pitt won last year's meeting vs Tennessee, 41-34, as a 3.5-point favorite.
• Pitt is 2-7 SU vs non-conference Power 5 opponents since 2016.

Tennessee vs Pittsburgh Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

This is a tricky spread as bettors will react to last week's results and how they saw Pitt struggle and pull out a fortunate win over rival West Virginia. But Pitt's well-regarded offensive and defensive line was out-played last week, and Tennessee is stronger. Vols coach Josh Heupel's offense is set to outscore last year's team that averaged 39.3 points per game.

Bet: Tennessee -6.5 (-114)