Syracuse vs Illinois Prediction, Odds & Best Bet for Nov. 29 (Fighting Illini Remain Dominant at State Farm Center)

Devon Platana
Syracuse vs. Illinois prediction, odds and betting insights for NCAA college basketball regular season game.
Syracuse vs. Illinois prediction, odds and betting insights for NCAA college basketball regular season game. / AP Photo/Michael Allio
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Syracuse vs Illinois Game Info

2022-23 NCAA College Basketball Regular Season Game
Syracuse Orange (3-3, 0-0 Away) vs. No. 16 Illinois Fighting Illini (5-1, 4-0 Home)
Date: Tuesday, Nov. 29, 2022
Time: 7:30 p.m. ET
Venue: State Farm Center — Champaign, IL
Coverage: ESPN

The 2022-23 NCAA college basketball season continues on Tuesday, Nov. 29, including an ACC/Big Ten Challenge matchup between the Syracuse Orange and No. 16 Illinois Fighting Illini.

Syracuse enters this game following a 73-72 loss to Bryant on Saturday, marking the Orange's second of back-to-back losses. Meanwhile, Illinois is riding a momentum wave after rebounding from its first loss of the season with a 92-59 blowout win over Lindenwood on Friday.

Can Syracuse finally snap its losing ways? Or will Illinois be too much of a challenge in front of its rowdy home crowd?

Syracuse vs Illinois Odds & Spread

All NCAA college basketball betting lines, odds and prop bets.
Moneyline: SYR: (+580) | ILL: (-880)
Spread: SYR: +12.5 (-110) | ILL: -12.5 (-110)
Total: 143.5 - Over: (-110) | Under: (-110)

Illinois enters this contest as the clear favorite on the moneyline and spread per FanDuel Sportsbook's odds. This 7:30 p.m. ET clash also features an over/under of 143.5 points, which is one of the highest of Tuesday's projected totals.

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Syracuse vs Illinois Prediction & Pick

Syracuse is a team that you simply can't trust on the road. While this is only the Orange's first away game of the campaign, they've lost eight of their last 10 road encounters. On the other hand, Illinois is a perfect 4-0 at State Farm Center this fall.

The Fighting Illini also have the edge on both offense and defense. Illinois' plus-23.2 point differential is the seventh-best in the nation, showcasing the team's ability to score the ball while keeping it out of its own basket. For comparison, Syracuse has a minus-1.7 differential over its last three games.

Factor in the Orange being a disappointing 3-6 against the spread (ATS) in their last nine games against the Big Ten, and it's easy to see why this is the Fighting Illini's game to lose.

Final Score Prediction: Illinois: 81 | Syracuse: 65

Syracuse vs Illinois Betting Trends

- Syracuse is 1-4 against the spread (ATS) in its last five games.
- Illinois is 6-0 straight up in its last six home games.
- The total has hit the under in four of Syracuse's last five games.
- The total has hit the over in four of Illinois' last five games against the ACC.

Syracuse vs Illinois Best Bet

Syracuse has struggled to live up to expectations this season, going 1-4 ATS in its last five outings. Meanwhile, Illinois is 4-1 ATS over the last five games while beating opponents by an average of 34.8 points at home.

Do I think the Fighting Illini will win by that much tonight? Probably not, but their offense and defense are more than good enough to cover the 12.5-point spread against the Orange.

Bet: Illinois -12.5 (-110)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.

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