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Steelers vs Bills Prediction, Odds & Betting Trends for NFL Week 5 Game on FanDuel Sportsbook

Devon Platana
Pittsburgh Steelers vs Buffalo Bills prediction, odds and betting trends for NFL Week 5.
Pittsburgh Steelers vs Buffalo Bills prediction, odds and betting trends for NFL Week 5. / ASSOCIATED PRESS
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Steelers vs Bills Week 5 Game Info

2022 NFL Regular Season Game
Pittsburgh Steelers (1-3, 1-1 Away) vs. Buffalo Bills (3-1, 1-0 Home)
Date: Sunday, Oct. 9, 2022
Time: 1 p.m. ET
Venue: Highmark Stadium — Orchard Park, NY
Coverage: CBS

Week 5 of the 2022 NFL season includes a showdown between the Pittsburgh Steelers and Buffalo Bills. After a season-opening win, the Steelers have now lost three straight games, with their most recent being a 24-20 loss to the lowly New York Jets.

Meanwhile, the Bills bounced back from their Week 3 loss in the form of a 23-20 victory over the Baltimore Ravens. It was a game without any real standout offensive performers for Buffalo, however, safety Jordan Poyer did lead the game in broken-up passes (three) and interceptions (two).

Steelers vs Bills Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: PIT: (+610) | BUF: (-900)
Spread: PIT: +14 (-110) | BUF: -14 (-110)
Total: 45.5 —Over: (-110) | Under: (-110)

Updated (Sunday, Oct. 9, 9:10 a.m. EST): The Bills remain massive home favorites on the moneyline and spread on FanDuel Sportsbook's updated odds, which haven't budged at all over the last few days. This 1 p.m. ET clash now features a total of 45.5 (down from 47.5), which is still among the highest of the projected Week 4 totals.

Steelers vs Bills Prediction & Pick

After what they've shown thus far, there isn't a reason to believe that the Steelers can upset the Bills here. Buffalo sits inside of the top 10 when it comes to scoring offense and defense, whereas Pittsburgh produces just 18.5 points per game, which is tied for eighth-worst in the NFL.

A lot of the Steelers' offensive issues can be attributed to Mitchell Trubisky under center. While Kenny Pickett could be an improvement, the rookie quarterback did record three interceptions in his NFL debut. In other words, it's tough to see either QB having success against a Bills defense that's amassed the second-most takeaways (nine) so far this season.

Expect the Bills to win this one decisively.

Final Score Prediction: Bills: 30 | Steelers: 14

Steelers vs Bills Betting Trends

- Pittsburgh is 1-4 straight up in its last five games.
- Buffalo is 4-1-1 against the spread (ATS) in its last six games as the favorite.
- The total has hit the over in six of Pittsburgh's last eight road games.
- The total has hit the under in each of Buffalo's last eight games against the AFC North.

Steelers vs Bills Best Bet

Again, the Steelers haven't given people a reason to think that this should be a close game. Mike Tomlin's team has given up 24-plus points to the Jets and Cleveland Browns over the last two weeks — two teams that aren't close to being on the Bills' level.

A 14-point spread is certainly daunting, but if there's any team that can cover, it's the BIlls.

Bet: Bills -14 (-110)

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Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

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