South Carolina vs Clemson Prediction, Odds & Best Bet for Week 13 (Gamecocks Rise to Challenge)

South Carolina vs Clemson Week 13 Game Info

2022 NCAA College Football Game
South Carolina (7-4) vs. Clemson Tigers (10-1)
Date: Saturday, Nov. 26, 2022
Time: 12 p.m. ET
Venue: Memorial Stadium — Clemson, SC
Coverage: ABC

Week 13 of the 2022 NCAA college football season includes a rivalry Battle in the Palmetto State between SEC's South Carolina Gamecocks and ACC's Clemson Tigers.

Clemson should hold steady at No. 8 when the College Football Playoff poll is released the evening of Nov. 22. The Tigers enter off blowout wins over Louisville and Miami to reach 10 wins, and have this rivalry game ahead of next Week's ACC Championship Game vs North Carolina.

Meanwhile, South Carolina comes off a huge win and trouncing of previous No. 1 Tennessee, 63-28.

South Carolina vs Clemson Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SC: (+450) | CLEM: (-630)
Spread: SC: +14.5 (-110) | CLEM: -14.5 (-110)
Total: 51.5 — Over: (-110) | Under: (-110)

Clemson enters this rivalry game as a big favorite on the spread (-14.5) and moneyline (-630). A South Carolina win returns +450. The line is down from Sunday's opener in Las Vegas of Clemson -16, and the total is up sharply from 47.5 and now sits at 51.5 points.

South Carolina vs Clemson Prediction & Pick

Clemson is very good, but not this good. They were exposed three weeks ago in a 35-14 loss at Notre Dame while gaining just 280 yards offense. Clemson also trailed to Syracuse 21-10 into the fourth quarter before escaping at home 27-21 a month ago. We've seen that Syracuse is not as good as they showed earlier in the season, and really neither is overrated Clemson.

Playing in the weakest Power 5 conference ACC, the Tigers are not CFB Playoff worthy, nor a good bet spotting these inflated points to a capable 'Cocks team who just took down Tennessee 63-38. One major tout service had Tennessee as its 'Game of the Year'. Ugh.

Inflation is never a good thing, and especially when betting on overvalued and overbet teams. Clemson as a slightly above average pass defense in the ACC, and the Tigers 412 yards per game offense ranks No. 6 in the ACC. In fact, vs FBS foes, the Tigers run for an average of 188 YPG and pass for 220 per game. That's pretty balanced and solid, but put Clemson in the SEC, and they too would have 3 or 4 losses like South Carolina.

South Carolina's run defense is a concern in this match-up, but not enough to worry about with these big points. Don't be shocked if South Carolina snaps Clemson's 10-game home winnning streak.

Final Score Prediction: South Carolina: 30 | Clemson: 27

South Carolina vs Clemson Betting Trends

- South Carolina 6-2 staight up (SU) in their last 8 games.
- South Carolina is 4-2 against the spread (ATS) in their last 6 games.
- South Carolina is 0-7 SU in their last 7 games vs Clemson.
- Clemson is 16-1 SU in their last 17 games.
- Clemson is 10-0 SU in their last 10 home games.
- Clemson is 5-2 ATS in their last 7 games.

South Carolina vs Clemson Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

South Carolina coach Shane Beamer is building better in Columbia. The Gamecocks offense and QB Spencer Rattler has struggled against stronger SEC defenses. But Rattler had the game of his life last week passing for 438 yards and 6 touchdowns.

Clemson won last year's meeting 30-0. The Tigers are 16-1 SU in their last 17 home games. All this is factored into the price, and the Tigers are overrated. You should take advantage in this rivalry game.

Bet: South Carolina +14.5 (-110) and Moneyline +450

Game odds refresh periodically and are subject to change.