Saints vs 49ers Opening Odds, Betting Lines & Prediction for Week 12 Game on FanDuel Sportsbook

Week 11 NFL action is underway, but FanDuel Sportsbook has already released NFL odds and lines for Week 12, giving us an early preview of the upcoming slate.

Week 12 includes a battle between the New Orleans Saints and San Francisco 49ers.

Saints vs 49ers Odds & Lines Week 12

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: NO: (+330) | SF: (-420)
Spread: NO: +8.5 (-110) | SF: -8.5 (-110)
Total: N/A — Over: (N/A) | Under: (N/A)

The 49ers are projected as massive home favorites in Week 12. San Francisco is an early -420 moneyline favorite and favored by 8.5 points on the spread.

Saints vs 49ers Prediction Week 12

Early NFL predictions and picks are from ESPN's Football Power Index (FPI).
Saints: 23.2% to win
49ers: 76.6% to win

The 49ers need to keep winning games to keep pace with the Seattle Seahawks in the NFC West race. The team has been helped greatly by the addition of Christian McCaffrey, winning two of the three games he's suited up in. On the other hand is a Saints squad that has no idea which side will show up. They played a shootout with the Los Angeles Rams in Week 11, but has scored less than 20 points in four games. San Francisco's defense makes it a fifth. Take 49ers on the ML.

Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.