RB Leipzig vs Manchester City Prediction, Odds & Best Bet for Champions League Match (Man City Shines on the Road)

Larry Rupp
RB Leipzig vs Manchester City prediction, odds and betting insights for Champions League match.
RB Leipzig vs Manchester City prediction, odds and betting insights for Champions League match. / AP Photos/Dave Thompson
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RB Leipzig vs Manchester City Match Info

2022-23 UEFA Champions League — Round of 16 (1st Leg)
RB Leipzig vs. Manchester City
Date: Wednesday, Feb. 22, 2023
Time: 3:00 p.m. ET
Venue: Red Bull Arena — Leipzig, Germany

RB Leipzig and Manchester City meet head-to-head in Champions League action on Wednesday, Feb. 22. This Round of 16 matchup will take place across two legs to determine which team will advance to the next stage. Each team will get a chance to play in front of its home crowd, with RB Leipzig up first.

RB Leipzig vs Manchester City Odds & Spread

All Champions League betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: LEIP: (+350) | MANC: (-140) | Draw (+300)
Spread: LEIP: +1 (+100) | MANC: -1 (+195)
Total: 2.5 – Over: (-174) | Under: (+142)
Team to Score the First Goal: LEIP: (+155) | MANC: (-190) I NO GOALS: (+1600)

Manchester City enters this contest as a clear road favorite on FanDuel Sportsbook's odds. This 3 p.m. ET clash also features an over/under of 2.5 goals with the over being favored at -174 odds.

RB Leipzig vs Manchester City Prediction & Pick

RB Leipzig dropped its first two matches in Champions League group play before coming to life and outscoring its opponent 12-3 over the final four matches. The team has been playing well and enters the Round of 16 with momentum, but it's facing one of the best squads left in contention for the title.

Manchester City allowed only 2 goals across six group stage matches, posting four clean sheets and tallying an average of 3.5 shots blocked per match. The consistency of goalkeeper Stefan Ortega was unmatched and presents RB Leipzig with an uphill battle to climb, even in front of the home fans.

Manchester City has too much talent on both ends of the pitch to fall victim to an upset here.

Final Score Prediction: RB Leipzig: 1 | Manchester City: 3

RB Leipzig vs Manchester City Betting Trends

- Manchester City is 1-0-1 (W-D-L) in two all-time Champions League matches against RB Leipzig.
- RB Leipzig finished second in Group F of the Champions League with a 4-0-2 (W-D-L) record.
- Manchester City finished first in Group G of the Champions League with a 4-2-0 (W-D-L) record.

RB Leipzig vs Manchester City Best Bet

Manchester City's defense stepped up in the group stage, but RB Leipzig has not been held without a single goal since September. Manager Marco Rose's will get the crowd going with an early score. The depth of Manchester City will still prove to be too much, though, which makes backing manager Pep Guardiola's team on the moneyline the way to go. Link it with both teams to score for a solid payout.

Bet: Man City ML & Both Teams to Score (+200)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.

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