Rams vs Chiefs Prediction, Odds & Best Bets for Week 12 (Kansas City Blows Out LA at Arrowhead Stadium)

Rams vs Chiefs Week 12 Game Info

2022 NFL Regular Season — Week 12
Los Angeles Rams (3-7, 1-3 Away) vs. Kansas City Chiefs (8-2, 4-1 Home)
Date: Sunday, Nov. 27, 2022
Time: 4:25 p.m. ET
Venue: GEHA Field at Arrowhead Stadium — Kansas City, MO
Coverage: FOX

The Los Angeles Rams will look to play spoiler when they visit the Kansas City Chiefs in Week 12 NFL action. The Rams have dropped each of their last four games, including a frustrating 27-20 loss to the New Orleans Saints on Sunday. Quarterback Matthew Stafford had to be removed with a concussion.

Meanwhile, the Chiefs extended their winning streak to four games after taking down the Los Angeles Chargers by a score of 30-27 in Week 11. It was another big day for tight end Travis Kelce, who tallied 115 yards and 3 touchdowns on 6 receptions. He now ranks sixth in the NFL in receiving yards (855).

Rams vs Chiefs Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: LAR: (+830) | KC: (-1400)
Spread: LAR: +15.5 (-108) | KC: -15.5 (-112)
Total: 42.5 — Over: (-105) | Under: (-115)

Updated (Sunday, Nov. 27, 11:50 a.m. EST): The Chiefs enter this contest as massive home favorites on the moneyline and the spread on FanDuel Sportsbook's updated odds. This 4:25 p.m. ET clash also features one of the lower totals on the Week 12 slate at 42.5 points.

Rams vs Chiefs Prediction & Pick

This is a matchup everyone had circled on their calendars coming into the season. However, injuries to Stafford as well as wide receiver Cooper Kupp leave the Rams entering Sunday as big underdogs. Keep in mind Los Angeles has beaten Kansas City just once in its last seven head-to-head matchups.

The major difference here is on offense. The Chiefs lead the NFL averaging 30.0 points per game and 6.5 yards per play. On the other side, the Rams rank ahead of only three other teams when it comes to scoring (16.8 points per game) and average a league-low 4.7 yards per play. It has been a rough year.

With Stafford ruled out and Patrick Mahomes ready to go, give me the Chiefs in a blowout.

Final Score Prediction: Rams: 14 | Chiefs: 31

Rams vs Chiefs Betting Trends

- The Rams are 2-9-1 against the spread (ATS) in its last 12 games.
- The total has hit the under in eight of the Rams' last 12 games.
- Kansas City is 6-1 straight up in its last seven games against the Rams.
- The total has hit the over in 12 of the Kansas City's last 18 games.

Rams vs Chiefs Best Bet

Backing a team to cover a spread over two touchdowns in the NFL is always risky because so many things could go wrong. However, this is truly a matchup between the league's best and worst offense. If there is a perfect time to trust a team to blow out their opponent, it is in Week 12 with Kansas City.

The Chiefs boast the best third-down conversion percentage in the NFL (51.7%) and own the third-best red zone scoring percentage (72.1%). They are keeping drives alive and capping them off with scores. The Rams are also 0-6-1 against the spread in their last seven games against the Chiefs.

Bet: Kansas City Chiefs -15.5 (-112)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.