Purdue vs West Virginia Prediction, Odds & Best Bet for Nov. 24 (Boilermakers Taken to the Limit by Mountaineers)

Purdue vs West Virginia Game Info

2022-23 NCAA College Basketball Regular Season Game
No. 24 Purdue Boilermakers (3-0) vs. West Virginia Mountaineers (4-0)
Date: Thursday, Nov. 24, 2022
Time: 10 p.m. ET
Venue: Veterans Memorial Coliseum — Portland, OR
Coverage: ESPN2

The 2022-23 NCAA college basketball season continues on Thursday, Nov. 24 with a Phil Knight Legacy opening-round matchup between the No. 24 Purdue Boiler Makers and West Virginia Mountaineers.

Down by as many as nine points, Purdue battled back to defeat Marquette, 75-70, in its last outing, improving to 3-0 this fall. Meanwhile, West Virginia's undefeated streak was kept alive thanks to a 92-58 win against Pennsylvania nearly one week ago.

Can Purdue further showcase why it deserves to be a top-25 program this season? Or will West Virginia run over its upcoming opponent like it has the others thus far?

Purdue vs West Virginia Odds & Spread

All NCAA college basketball betting lines, odds and prop bets.
Moneyline: PUR: (-134) | WVU: (+112)
Spread: PUR: -2.5 (-105) | WVU: +2.5 (-115)
Total: 134.5 —Over: (-114) | Under: (-106)

Purdue enters this contest as the slight favorite on the moneyline and spread per FanDuel Sportsbook's odds. This 10 p.m. ET clash also features an over/under of 134.5 points, which is among the lowest of Thursday's projected totals.

Purdue vs West Virginia Prediction & Pick

This meeting marks the ninth time that Purdue and West Virginia will meet, as well as the first clash since 2013. The Boilermakers have absolutely dominated the all-time series, winning seven of the previous matchups — including the last two by a margin of 30 total points.

Both schools own top-30 scoring defenses this season and while West Virginia is worse at defending the perimeter, the Boilermakers can't shoot from range. Purdue only averages 7.7 threes per game (T-No. 145) with a 28.8% success rate (T-No. 299).

Even with Purdue's three-point defense being better, the team did allow Marquette to shoot 11-of-35 (31.4%) from three-point range. With West Virginia going 12-of-23 (52.2%) from beyond the arc in its last outing, I think the makings of an upset are here.

Back West Virginia squeaking out with a close-fought win.

Final Score Prediction: West Virginia: 70 | Purdue: 67

Purdue vs West Virginia Betting Trends

- Purdue is 3-10 against the spread (ATS) in its last 13 games.
- West Virginia is 7-0 straight up in its last seven games played in November.
- The total has hit the over in each of Purdue's last seven games against the Big 12.
- The total has hit the over in five of West Virginia's last six games.

Purdue vs West Virginia Best Bet

Purdue being 3-10 against the spread in its last 13 games makes the team incredibly tough to trust. However, taking West Virginia on the spread doesn't provide much value. Instead, a moneyline bet is more playable in the event of an upset, meaning you should back the Mountaineers at +112 odds on the moneyline.

Bet: West Virginia ML (+112)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.