Padres vs Dodgers Prediction, Odds, Betting Trends & Probable Pitchers for NLDS Game 1 MLB Playoffs

Padres vs Dodgers Game 1 Info

2022 MLB Playoffs — NLDS Game 1
No. 5 San Diego Padres (89-73, 45-36 Away) vs. No. 1 Los Angeles Dodgers (111-51, 57-24 Home)
Date: Tuesday, October 11, 2022
Time: 9:37 p.m. ET
Venue: Dodger Stadium — Los Angeles, CA
Coverage: FS1

The NLDS round of the 2022 MLB Playoffs features a pair of exciting matchups, including a divisional showdown between the 5-seed San Diego Padres and 1-seed Los Angeles Dodgers. The Padres took down the New York Mets in the Wild Card Round thanks to a marvelous outing by starting pitcher Joe Musgrove in Game 3.

Meanwhile, the Dodgers' hunt for a seventh NLCS appearance in the last 10 years starts on Tuesday night. Los Angeles won a league-best 111 games in the regular season, which was the most by any National League team in over a century. This is a team built around an elite pitching staff as well as a powerful lineup.

Padres vs Dodgers Odds & Spread

All MLB Postseason betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SD: (+176) | LAD: (-210)
Spread: SD: +1.5 (-125) | LAD: -1.5 (+104)
Total: 6.5 — Over: (-110) | Under: (-110)

The Dodgers enter this contest as a clear home favorite on the moneyline and spread. They are listed at -210 moneyline odds with +104 odds to cover the 1.5-run spread. The over/under on this matchup features a low 6.5 runs, notably because of the strength of the starting pitchers for each side.

Padres vs Dodgers Prediction & Pick

Don't get it twisted, the Padres are a dangerous team. That doesn't have to be reiterated about a lineup that includes the likes of Manny Machado and Juan Soto. It's important to remember that LA has simply dominated San Diego in 2022, though, posting a 14-5 record in head-to-head meetings. Take into account the Dodgers home record (57-24) and it becomes clear they are the pick here.

This one comes down to the Dodgers' ability to score runs in bunches. They averaged a league-best 5.23 runs per game in the regular season and are set to face Mike Clevinger in Game 1. Clevinger owns a dismal 9.69 ERA and 1.54 WHIP across three starts against LA in 2022. The Dodgers know how to work counts and find gaps in the field, so this could end up as a rare postseason blowout.

Final Score Prediction: Padres: 2 | Dodgers: 7

Padres vs Dodgers Probable Starting Pitchers

Note: The Dodgers have yet to release their official probable pitcher. The below is a projection outlined from Dodgers insider Juan Toribio.

The San Diego Padres will look to Mike Clevinger (7-7, 4.33 ERA) in Game 1 and the Los Angeles Dodgers hand the ball to either Clayton Kershaw (12-3, 2.28 ERA) ERA) or Julio Urias (17-7, 2.16 ERA).

Padres vs Dodgers Betting Trends

- San Diego is 8-4 straight up in its last 12 games against a NL West opponent.
- The total has hit the over in four of San Diego's last five away games.
- The Dodgers are 4-1 straight up in its last five games against the Dodgers.
- The total has hit the under in four of the Dodgers' last five home games.

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.