Orioles vs Yankees Prediction, Odds & Best Bet for May 23 (Can Baltimore's Hitters Figure Out Gerrit Cole?)

Two teams vying to keep pace in a tough American League East division meet head-to-head on Tuesday, May 23, as the Baltimore Orioles (31-16) travel to take on the New York Yankees (29-20).

Orioles vs Yankees Game Info

• Date: Tuesday, May 23, 2023
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium – Bronx, NY
• Coverage: YES Network and MASN

This is the second series of the season in which these AL East teams have faced off as New York took two of three games in Baltimore in early April. Both teams enter Tuesday with momentum as the Orioles have won five of their last six games and the Yankees have won six of their last seven games.

Orioles vs Yankees Odds & Spread

• All MLB betting lines, odds and prop bets are from FanDuel Sportsbook.
• Moneyline: BAL: (+142) | NYY: (-168)
• Spread: BAL: +1.5 (-152) | NYY: -1.5 (+126)
• Total: 7.5 -- Over: (-118) | Under: (-104)

The Yankees enter this contest as home favorites on the moneyline per FanDuel Sportsbook's odds. This 7:05 p.m. ET clash also features an over/under of 7.5 runs with the over favored at -118 odds.

Orioles vs Yankees Betting Trends

• Baltimore is 12-4 straight up in its last 16 away games.
• The total has hit the over in five of Baltimore's last seven games.
• The Yankees are 6-3 straight up in their last nine home games against Baltimore.
• The total has hit the under in four of the Yankees' last five games.

Orioles vs Yankees Prediction & Pick

The Orioles were labeled as a sneaky playoff contender heading into the regular season, but they have even exceeded those expectations early on. They will look to keep the good vibes going with Kyle Bradish, who is 2-1 on the year with a 3.90 ERA and 1.30 WHIP, on the mound against New York.

The Yankees will counter with their ace Gerrit Cole. The 32-year-old has been dominant so far with a 2.01 ERA and 1.09 WHIP across 10 starts (5-0 record). He did not pitch against the Orioles during the April series, but did struggle against them in 2023 with a 4.29 ERA across three starts (1-2 record).

Cole's past struggles against Baltimore make this pitching matchup a wash, so focusing on the two offenses is crucial. Baltimore is tallying the third-most runs per away game (5.83), while the Yankees own the ninth-worst on-base percentage at home (0.314). That's enough for me to back an upset.

Final Score Prediction: Orioles: 5 | Yankees: 4

Orioles vs Yankees Best Bet

This Orioles lineup features three different hitters with at least 13 plate appearances and at least a .318 batting average against Cole in their career (Mullins, Hays & McCann). Not only that, but it's a lineup that has scored at least 4 runs in six of the last seven games. Baltimore even scored 3 runs in the only performance in which they missed the mark. Taking on slightly juiced odds is worth it here.

Bet: Baltimore Orioles Over 3 Runs (-132)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.