NFL Week 2 Picks & Predictions Against the Spread From The Duel Staff (2022)

The 2022 NFL season is rolling along for Week 2 and the editors at The Duel are making against the spread (ATS) picks for each and every game. You can follow along, check it out or fade us throughout the season.

NFL Week 2 Predictions

We have full betting previews for each matchup below along with the betting lines from FanDuel Sportsbook. We’ll update this with records on a weekly basis and make picks for every step of the way, including the playoffs and Super Bowl.

NFL Expert Picks Against the Spread

Note: All betting lines and odds are from FanDuel Sportsbook, as of Wednesday, Sept. 14 at 2 p.m. EST.

Chargers vs Chiefs Picks

Chargers (+4.5) vs Chiefs (-4.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Chiefs
- Taylor McKillop: Chiefs
- David Kaestle: Chiefs
- Isaiah De Los Santos: Chargers
- Jason Schandl: Chiefs
- Tyler Maher: Chiefs

Commanders vs Lions Picks

Commanders (+1.5) vs Lions (-1.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Lions
- Taylor McKillop: Commanders
- David Kaestle: Lions
- Isaiah De Los Santos: Commanders
- Jason Schandl: Lions
- Tyler Maher: Lions

Jets vs Browns Picks

Jets (+5.5) vs Browns (-5.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Browns
- Taylor McKillop: Jets
- David Kaestle: Jets
- Isaiah De Los Santos: Browns
- Jason Schandl: Browns
- Tyler Maher: Jets

Buccaneers vs Saints Picks

Buccaneers (-2.5) vs Saints (+2.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Saints
- Taylor McKillop: Buccaneers
- David Kaestle: Buccaneers
- Isaiah De Los Santos: Saints
- Jason Schandl: Buccaneers
- Tyler Maher: Buccaneers

Panthers vs Giants Picks

Panthers (+1.5) vs Giants (-1.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Giants
- Taylor McKillop: Giants
- David Kaestle: Giants
- Isaiah De Los Santos: Panthers
- Jason Schandl: Giants
- Tyler Maher: Panthers

Patriots vs Steelers Picks

Patriots (-1.5) vs Steelers (+1.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Patriots
- Taylor McKillop: Patriots
- David Kaestle: Steelers
- Isaiah De Los Santos: Steelers
- Jason Schandl: Patriots
- Tyler Maher: Steelers

Colts vs Jaguars Picks

Colts (-4.5) vs Jaguars (+4.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Colts
- Taylor McKillop: Jaguars
- David Kaestle: Colts
- Isaiah De Los Santos: Colts
- Jason Schandl: Jaguars
- Tyler Maher: Colts

Dolphins vs Ravens Picks

Dolphins (+3.5) vs Ravens (-3.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Ravens
- Taylor McKillop: Dolphins
- David Kaestle: Dolphins
- Isaiah De Los Santos: Dolphins
- Jason Schandl: Dolphins
- Tyler Maher: Ravens

Falcons vs Rams Picks

Falcons (+10.5) vs Rams (-10.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Falcons
- Taylor McKillop: Falcons
- David Kaestle: Rams
- Isaiah De Los Santos: Falcons
- Jason Schandl: Falcons
- Tyler Maher: Rams

Seahawks vs 49ers Picks

Seahawks (+9.5) vs 49ers (-9.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: 49ers
- Taylor McKillop: Seahawks
- David Kaestle: 49ers
- Isaiah De Los Santos: Seahawks
- Jason Schandl: Seahawks
- Tyler Maher: Seahawks

Bengals vs Cowboys Picks

Bengals (-7.5) vs Cowboys (+7.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Bengals
- Taylor McKillop: Bengals
- David Kaestle: Bengals
- Isaiah De Los Santos: Bengals
- Jason Schandl: Bengals
- Tyler Maher: Cowboys

Texans vs Broncos Picks

Texans (+9.5) vs Broncos (-9.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Texans
- Taylor McKillop: Texans
- David Kaestle: Broncos
- Isaiah De Los Santos: Texans
- Jason Schandl: Broncos
- Tyler Maher: Broncos

Cardinals vs Raiders Picks

Cardinals (+5.5) vs Raiders (-5.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Raiders
- Taylor McKillop: Cardinals
- David Kaestle: Raiders
- Isaiah De Los Santos: Cardinals
- Jason Schandl: Cardinals
- Tyler Maher: Cardinals

Bears vs Packers Picks

Bears (+9.5) vs Packers (-9.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Packers
- Taylor McKillop: Packers
- David Kaestle: Packers
- Isaiah De Los Santos: Bears
- Jason Schandl: Packers
- Tyler Maher: Packers

Titans vs Bills Picks

Titans (+9.5) vs Bills (-9.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Titans
- Taylor McKillop: Bills
- David Kaestle: Titans
- Isaiah De Los Santos: Bills
- Jason Schandl: Bills
- Tyler Maher: Titans

Vikings vs Eagles Picks

Vikings (+1.5) vs Eagles (-1.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Eagles
- Taylor McKillop: Eagles
- David Kaestle: Vikings
- Isaiah De Los Santos: Vikings
- Jason Schandl: Eagles
- Tyler Maher: Eagles

Staff Records (ATS):
- Jason Schandl: 10-6 (62.50%)
- David Kaestle: 10-6 (62.50%)
- Isaiah De Los Santos: 9-7 (56.25%)
- Taylor McKillop: 7-9 (43.75%)
- Tyler Maher: 5-11 (31.25%)
- Brian Giuffra: 0-0 (00.00%)

Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.