NFL Week 1 Picks & Predictions Against the Spread From The Duel Staff (2022)

The 2022 NFL season is finally here and the editors at The Duel are making against the spread (ATS) picks for each and every game. You can follow along, check it out, or fade us throughout the season.
NFL Week 1 Predictions
We have full betting previews for each matchup below along with the betting lines from FanDuel Sportsbook. We’ll update this with records on a weekly basis and make picks for every step of the way, including the playoffs and Super Bowl.
NFL Expert Picks Against the Spread
Note: All betting lines and odds are from FanDuel Sportsbook, as of Wednesday, Sept. 7 at 5 p.m. EST.
Bills vs Rams Picks
Bills (-2.5) vs Rams (+2.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Rams
- David Kaestle: Bills
- Isaiah De Los Santos: Bills
- Jason Schandl: Rams
- Tyler Maher: Bills
Steelers vs Bengals Picks
Steelers (+6.5) vs Bengals (-6.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Steelers
- David Kaestle: Steelers
- Isaiah De Los Santos: Bengals
- Jason Schandl: Bengals
- Tyler Maher: Bengals
Eagles vs Lions Picks
Eagles (-3.5) vs Lions (+3.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Eagles
- David Kaestle: Lions
- Isaiah De Los Santos: Eagles
- Jason Schandl: Lions
- Tyler Maher: Eagles
Colts vs Texans Picks
Colts (-7.5) vs Texans (+7.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Colts
- David Kaestle: Texans
- Isaiah De Los Santos: Colts
- Jason Schandl: Texans
- Tyler Maher: Colts
Saints vs Falcons Picks
Saints (-5.5) vs Falcons (+5.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Saints
- David Kaestle: Saints
- Isaiah De Los Santos: Falcons
- Jason Schandl: Falcons
- Tyler Maher: Saints
Ravens vs Jets Picks
Ravens (-6.5) vs Jets (+6.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Ravens
- David Kaestle: Ravens
- Isaiah De Los Santos: Ravens
- Jason Schandl: Ravens
- Tyler Maher: Ravens
Patriots vs Dolphins Picks
Patriots (+3.5) vs Dolphins (-3.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Dolphins
- David Kaestle: Patriots
- Isaiah De Los Santos: Dolphins
- Jason Schandl: Patriots
- Tyler Maher: Patriots
Browns vs Panthers Picks
Browns (+1.5) vs Panthers (-1.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Browns
- David Kaestle: Panthers
- Isaiah De Los Santos: Browns
- Jason Schandl: Browns
- Tyler Maher: Panthers
49ers vs Bears Picks
49ers (-6.5) vs Bears (+6.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: 49ers
- David Kaestle: 49ers
- Isaiah De Los Santos: 49ers
- Jason Schandl: 49ers
- Tyler Maher: 49ers
Jaguars vs Commanders Picks
Jaguars (+2.5) vs Commanders (-2.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Commanders
- David Kaestle: Commanders
- Isaiah De Los Santos: Commanders
- Jason Schandl: Commanders
- Tyler Maher: Commanders
Raiders vs Chargers Picks
Raiders (+3.5) vs Chargers (-3.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Raiders
- David Kaestle: Chargers
- Isaiah De Los Santos: Raiders
- Jason Schandl: Chargers
- Tyler Maher: Chargers
Giants vs Titans Picks
Giants (+5.5) vs Titans (-5.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Titans
- David Kaestle: Giants
- Isaiah De Los Santos: Giants
- Jason Schandl: Giants
- Tyler Maher: Titans
Chiefs vs Cardinals Picks
Chiefs (-5.5) vs Cardinals (+5.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Chiefs
- David Kaestle: Chiefs
- Isaiah De Los Santos: Cardinals
- Jason Schandl: Chiefs
- Tyler Maher: Cardinals
Packers vs Vikings Picks
Packers (-1.5) vs Vikings (+1.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Packers
- David Kaestle: Packers
- Isaiah De Los Santos: Vikings
- Jason Schandl: Packers
- Tyler Maher: Packers
Buccaneers vs Cowboys Picks
Buccaneers (-2.5) vs Cowboys (+2.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Buccaneers
- David Kaestle: Buccaneers
- Isaiah De Los Santos: Buccaneers
- Jason Schandl: Cowboys
- Tyler Maher: Buccaneers
Broncos vs Seahawks Picks
Broncos (-6.5) vs Seahawks (+6.5) Betting Preview
Staff Picks (ATS):
- Taylor McKillop: Broncos
- David Kaestle: Broncos
- Isaiah De Los Santos: Broncos
- Jason Schandl: Seahawks
- Tyler Maher: Broncos
Staff Records (ATS):
- Brian Giuffra: 0-0 (00.00%)
- Taylor McKillop: 0-0 (00.00%)
- David Kaestle: 0-0 (00.00%)
- Isaiah De Los Santos: 0-0 (00.00%)
- Jason Schandl: 0-0 (00.00%)
- Tyler Maher: 0-0 (00.00%)
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Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.