NFL Week 1 Picks & Predictions Against the Spread From The Duel Staff (2022)

The 2022 NFL season is finally here and the editors at The Duel are making against the spread (ATS) picks for each and every game. You can follow along, check it out, or fade us throughout the season.

NFL Week 1 Predictions

We have full betting previews for each matchup below along with the betting lines from FanDuel Sportsbook. We’ll update this with records on a weekly basis and make picks for every step of the way, including the playoffs and Super Bowl.

NFL Expert Picks Against the Spread

Note: All betting lines and odds are from FanDuel Sportsbook, as of Wednesday, Sept. 7 at 5 p.m. EST.

Bills vs Rams Picks

Bills (-2.5) vs Rams (+2.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Rams
- David Kaestle: Bills
- Isaiah De Los Santos: Bills
- Jason Schandl: Rams
- Tyler Maher: Bills

Steelers vs Bengals Picks

Steelers (+6.5) vs Bengals (-6.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Steelers
- David Kaestle: Steelers
- Isaiah De Los Santos: Bengals
- Jason Schandl: Bengals
- Tyler Maher: Bengals

Eagles vs Lions Picks

Eagles (-3.5) vs Lions (+3.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Eagles
- David Kaestle: Lions
- Isaiah De Los Santos: Eagles
- Jason Schandl: Lions
- Tyler Maher: Eagles

Colts vs Texans Picks

Colts (-7.5) vs Texans (+7.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Colts
- David Kaestle: Texans
- Isaiah De Los Santos: Colts
- Jason Schandl: Texans
- Tyler Maher: Colts

Saints vs Falcons Picks

Saints (-5.5) vs Falcons (+5.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Saints
- David Kaestle: Saints
- Isaiah De Los Santos: Falcons
- Jason Schandl: Falcons
- Tyler Maher: Saints

Ravens vs Jets Picks

Ravens (-6.5) vs Jets (+6.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Ravens
- David Kaestle: Ravens
- Isaiah De Los Santos: Ravens
- Jason Schandl: Ravens
- Tyler Maher: Ravens

Patriots vs Dolphins Picks

Patriots (+3.5) vs Dolphins (-3.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Dolphins
- David Kaestle: Patriots
- Isaiah De Los Santos: Dolphins
- Jason Schandl: Patriots
- Tyler Maher: Patriots

Browns vs Panthers Picks

Browns (+1.5) vs Panthers (-1.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Browns
- David Kaestle: Panthers
- Isaiah De Los Santos: Browns
- Jason Schandl: Browns
- Tyler Maher: Panthers

49ers vs Bears Picks

49ers (-6.5) vs Bears (+6.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: 49ers
- David Kaestle: 49ers
- Isaiah De Los Santos: 49ers
- Jason Schandl: 49ers
- Tyler Maher: 49ers

Jaguars vs Commanders Picks

Jaguars (+2.5) vs Commanders (-2.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Commanders
- David Kaestle: Commanders
- Isaiah De Los Santos: Commanders
- Jason Schandl: Commanders
- Tyler Maher: Commanders

Raiders vs Chargers Picks

Raiders (+3.5) vs Chargers (-3.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Raiders
- David Kaestle: Chargers
- Isaiah De Los Santos: Raiders
- Jason Schandl: Chargers
- Tyler Maher: Chargers

Giants vs Titans Picks

Giants (+5.5) vs Titans (-5.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Titans
- David Kaestle: Giants
- Isaiah De Los Santos: Giants
- Jason Schandl: Giants
- Tyler Maher: Titans

Chiefs vs Cardinals Picks

Chiefs (-5.5) vs Cardinals (+5.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Chiefs
- David Kaestle: Chiefs
- Isaiah De Los Santos: Cardinals
- Jason Schandl: Chiefs
- Tyler Maher: Cardinals

Packers vs Vikings Picks

Packers (-1.5) vs Vikings (+1.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Packers
- David Kaestle: Packers
- Isaiah De Los Santos: Vikings
- Jason Schandl: Packers
- Tyler Maher: Packers

Buccaneers vs Cowboys Picks

Buccaneers (-2.5) vs Cowboys (+2.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Buccaneers
- David Kaestle: Buccaneers
- Isaiah De Los Santos: Buccaneers
- Jason Schandl: Cowboys
- Tyler Maher: Buccaneers

Broncos vs Seahawks Picks

Broncos (-6.5) vs Seahawks (+6.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Broncos
- David Kaestle: Broncos
- Isaiah De Los Santos: Broncos
- Jason Schandl: Seahawks
- Tyler Maher: Broncos

Staff Records (ATS):
- Brian Giuffra: 0-0 (00.00%)
- Taylor McKillop: 0-0 (00.00%)
- David Kaestle: 0-0 (00.00%)
- Isaiah De Los Santos: 0-0 (00.00%)
- Jason Schandl: 0-0 (00.00%)
- Tyler Maher: 0-0 (00.00%)

Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.