NCAA Tournament Underdogs Sweet 16 for March Madness 2021 Odds

Updated: Sep 10, 5:00pm UTC

With the entire first two rounds of the 2021 NCAA March Madness Tournament set, all 16 teams have punched their ticket to this year's Sweet 16 across the state of Indiana.

However, after a historic weekend of upsets, we still have plenty of underdogs and even some Cinderellas left in the mix looking ahead to this Saturday's action. Here's a full look at all of the underdogs left in this year's NCAA Tournament, ranked by odds to win March Madness 2021.

March Madness Underdogs Remaining

All March Madness betting odds and spreads are available on FanDuel Sportsbook.

Last Updated:Tuesday, March 23 @ 3 p.m. EST

1. No. 15 Oral Roberts

Odds to Win NCAA Tournament: (+10000)
Sweet 16 Matchup Odds: Oral Roberts (+11.5) | Arkansas (-11.5)

2. No. 12 Oregon State

Odds to Win NCAA Tournament: (+7000)
Sweet 16 Matchup Odds: Oregon State (+6.5) | Loyola Chicago (-6.5)

3. No. 11 Syracuse

Odds to Win NCAA Tournament: (+6000)
Sweet 16 Matchup Odds Syracuse (+6) | Houston (-6)

4. No. 5 Creighton

Odds to Win NCAA Tournament: (+5500)
Sweet 16 Matchup Odds: Creighton (+13.5) | Gonzaga (-13.5)

5. No. 11 UCLA

Odds to Win NCAA Tournament: (+5500)
Sweet 16 Matchup Odds: UCLA (+6) | Alabama (-6)

6. No. 7 Oregon

Odds to Win NCAA Tournament: (+4000)
Sweet 16 Matchup Odds: Oregon (+2.5) | USC (-2.5)

7. No. 5 Villanova

Odds to Win NCAA Tournament: (+3500)
Sweet 16 Matchup Odds: Villanova (+6.5) | Baylor (-6.5)

8. No. 4 Florida State

Odds to Win NCAA Tournament: (+2500)
Sweet 16 Matchup Odds: Florida State (+3) | Michigan (-3)

David Hayes is not a FanDuel employee. In addition to providing DFS gameplay advice, David Hayes also participates in DFS contests on FanDuel using his personal account, username DavidWHayes. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.