Missouri vs Mississippi State Prediction, Odds & Best Bet for February 21 (Can the Tigers Avoid a Season Sweep?)

Larry Rupp
Missouri vs Mississippi State prediction, odds and betting insights for NCAA college basketball regular season game.
Missouri vs Mississippi State prediction, odds and betting insights for NCAA college basketball regular season game. / AP Photos/Sam Craft

Missouri vs Mississippi State Game Info

  • 2022-23 NCAA Basketball Regular Season Game
  • Missouri (19-8, 7-7 SEC) vs. Mississippi State (18-9, 6-8 SEC)
  • Date: Tuesday, February 21, 2023
  • Time: 7:00 PM ET
  • Venue: Mizzou Arena -- Columbia, Missouri
  • Coverage: SEC Network

The 2022-23 college basketball season continues on Tuesday with an exciting matchup between the Mississippi State Bulldogs and Missouri Tigers. Mississippi State beat Ole Miss by a score of 69-61 on Saturday to earn its sixth win in its last seven games. Tolu Smith tallied 17 points and 12 rebounds.

Meanwhile, Missouri fell short in a 69-60 loss to Texas A&M on Saturday to suffer its third loss in its last five games. Kobe Brown lit up the scoreboard with 24 points (8-of-13 shooting), but the Tigers shot just 39.2% from the floor as a team. Which Big 12 school will emerge victorious on Tuesday?

Missouri vs Mississippi State Odds & Spread

Missouri enters this contest as a slight home favorite on the moneyline and spread per FanDuel Sportsbook's odds. This 7 p.m. ET clash also features an over/under of 138.5 points, which is about average compared to Tuesday's projected totals.

Missouri vs Mississippi State Betting Trends

  • Missouri has beaten the spread 13 times in 25 games.
  • The Tigers have an ATS record of 7-6 as 2.5-point favorites or more.
  • Out of 25 Missouri's games so far this year, 13 have hit the over.
  • Mississippi State's record against the spread is 14-13-0.
  • The Bulldogs' ATS record as 2.5-point underdogs or more is 3-2.
  • Mississippi State has seen 10 of its 27 games hit the over.
Missouri Rank Missouri AVG Mississippi State AVG Mississippi State Rank
21st 80.3 Points Scored 65.9 320th
327th 75.5 Points Allowed 59.3 6th
352nd 27.8 Rebounds 34.9 33rd
216th 8.1 Off. Rebounds 11.5 10th
20th 9.4 3pt Made 5.6 332nd
17th 16.4 Assists 14.6 80th
70th 10.9 Turnovers 12 187th

Missouri vs Mississippi State Prediction & Pick

These two teams met on Feb. 4 in what turned out to be a 63-52 win for Mississippi State. Missouri shot dismal 32.0% shooting percentage from the floor and committed 15 turnovers. The Bulldogs' defense was suffocating and should be able to replicate that success in a road matchup on Tuesday.

Mississippi State has posted the second-best defensive efficiency mark in the country when playing on the road. It can also limit Missouri's greatest offensive strength. The Tigers average 9.4 made threes per game, but the Bulldogs allow a three-point percentage of only 30.0% (No. 20 in NCAA).

Missouri has lost seven straight games to Mississippi State, too, so fade the Tigers in this one.

Final Score Prediction: Missouri: 67 | Mississippi State: 71

Missouri vs Mississippi State Best Bet

Mississippi State enters this game with a ton of positive momentum. The Bulldogs are 7-1 against the spread (ATS) in their last eight games overall and 5-0 ATS in their last five away games. They are also an amazing 12-1 ATS in their last 13 games against the Tigers. That is the definition of dominance.

Missouri is 1-4 ATS in its last five games overall and 4-8 ATS in its last 12 games against an SEC foe. Not only that, but the Tigers have lost four of their last five home games against the Bulldogs. While bettors looking for a bigger payout can back the moneyline here, taking the points is the best option.

Bet: Mississippi State Bulldogs +3.5 (-110)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.