Louisville vs Iowa Prediction, Odds & Best Bet for March 26 NCAA Women's Tournament Game (Hawkeyes Dominate)

Louisville vs Iowa Game Info

• 2022-23 NCAA Women's Tournament Game
• No. 5 Louisville (26-11) vs. No. 2 Iowa (29-6)
• Date: Sunday, March 26, 2023
• Time: 9 p.m. ET
• Venue: Climate Pledge Arena -- Seattle, WA
• Coverage: ESPN

The 2022-23 NCAA Women's Tournament continues with an Elite 8 Seattle 4 matchup between the No. 5 Louisville Cardinals and No. 2 Iowa Hawkeyes.

Louisville advanced past the Sweet 16 with a 72-62 win over No. 8 Ole Miss, highlighted by Hailey Van Lith's 21-point effort. On the other side, Caitlin Clark dropped 31 points with four three-pointers in Iowa's impressive 87-77 win against No. 6 Colorado.

Which side is destined to make it to the Final Four?

Louisville vs Iowa Odds & Spread

• All women's college basketball betting lines, odds and prop bets are from FanDuel Sportsbook.
• Moneyline: LOU: (+180) | IOWA: (-226)
• Spread: LOU: +5.5 (-115) | IOWA: -5.5 (-105)
• Total: 154.5 -- Over: (-110) | Under: (-110)

Iowa enters this contest as a clear favorite on the moneyline and spread per FanDuel Sportsbook's odds. This 9 p.m. ET clash also features an over/under of 154.5 points with both sides being available at -110 odds.

Louisville vs Iowa Prediction & Pick

Iowa has been blistering hot since December. The Hawkeyes are 24-3 straight up in their last 27 outings and have won seven straight games ahead of Sunday's matchup. What's even more impressive is that they've outscored opponents by an average of 17.1 points during their current winning streak.

Louisville has gotten by with a strong defense that surrenders 63.4 PPG, but it's not unbeatable. After all, the Cardinals allowed No. 12 Drake to drop 81 points on 51.8% shooting in the first round. Considering how Iowa is averaging 87.4 points over its last 14 games, I wouldn't be shocked if the Hawkeyes found offensive success.

Both teams deserve to be in the Elite 8, but it's Iowa that's better suited to move on. The Hawkeyes are playing their best basketball of the season and the Cardinals will learn that the hard way.

Final Score Prediction: Iowa: 81 | Louisville: 73

Louisville vs Iowa Best Bet

I'm siding with Iowa on the spread as the best bet here. The Hawkeyes own one of the most exciting offenses in the country and can score against even the best defenses. Their elite attack is a big reason why they've averaged just over 17 more points than their opponents over the last four months.

As great as Louisville can be, it won't keep things close this weekend.

Bet: Iowa -5.5 (-105)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.