Louisiana Tech vs Clemson Prediction, Odds & Betting Trends for College Football Week 3 Game on FanDuel

Louisiana Tech vs Clemson Week 3 Game Info

2022 NCAA College Football Game
Louisiana Tech (1-1) vs. No. 5 Clemson Tigers (2-0)
Date: Saturday, Sept. 17, 2022
Time: 8:00 p.m. ET
Venue:  Memorial Stadium -- Clemson, SC
Coverage: ACC Network

Week 3 of the 2022 NCAA college football season includes a Saturday night non-conference game between Conference USA's Louisiana Tech Bulldogs and the No. 5-ranked ACC kingpin Clemson Tigers. Watch and wager on FanDuel Sportsbook as you follow the action on the ACC Network.

Louisiana Tech and Clemson meet for the first time since 2006. The Tigers have won 39 straight regular-season games against Group of 5 opponents, so can they extend that streak to 40 with another win here?

Louisiana Tech vs Clemson Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: LT: (3500) | CLEM: (-10000)
Spread: LT: +33.5 (-106) | CLEM: -33.5 (-114)
Total: 52.5 — Over: (-112) | Under: (-108)

Clemson enters as a huge -33.5 point home favorite and -10000 on the moneyline. The total of 52.5 is a bit below average compared to some of the other lines we're seeing for Week 3.

Louisiana Tech vs Clemson Prediction & Pick

Louisiana Tech has had a rollercoaster season thus far. After getting blasted by Missouri, 52-24, in their season opener, they bounced back with a dominant 52-17 win over Stephen F. Austin last week. While their defense was horrendous during the first game, their offense caught fire during the second game and racked up an impressive 299 yards on the ground.

Clemson has been far more consistent, winning by scores of 41-10 over Georgia Tech and 35-12 against Furman. The Tigers' offense has yet to truly take off, however, falling short of 400 yards in both games.

That said, Clemson shouldn't have much of a problem taking care of business at home against a weaker opponent.

Final Score Prediction: Clemson: 41 | Louisiana Tech: 10

Louisiana Tech vs Clemson Betting Trends

• Louisiana Tech is 2-8 straight up (SU) in their last 10 games.
• Louisiana Tech is 2-7 against the spread (ATS) in their last 9 games.
• Clemson is 8-0 SU in their last 8 games.
• Clemson is 10-0 SU in their last 10 home games.
• Clemson is 4-1 ATS in their last 5 games.
• The total has gone Under in 4 of Clemson's last 5 games.

Louisiana Tech vs Clemson Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

Clemson has their ACC opener on deck at Wake Forest after this game. While the Tigers could blow out the Bulldogs, don't expect them to be as fully engaged. Their backups could also see some playing time in the fourth quarter if they have the game in hand. Clemson is coming off a mildly disappointing performance against Furman and could be headed for a similar showing here.

It's not easy to support a defenseless underdog, but that's the lean on Louisiana Tech.

Bet: Under Louisiana Tech +33.5 (-106)