Iowa vs Ohio State Prediction, Odds & Betting Trends for College Football Week 8 Game on FanDuel Sportsbook

Iowa vs Ohio State Week 8 Game Info

2022 NCAA College Football Game
Iowa Hawkeyes (3-3, 1-2 Big Ten) vs. No. 2 Ohio State Buckeyes (6-0, 3-0 Big Ten)
Date: Saturday, Oct. 22, 2022
Time: 12:00 p.m. ET
Venue: Ohio Stadium -- Columbus, OH
Coverage: FOX

Week 8 of the 2022 NCAA college football season includes an Big Ten cross division battle between the Iowa Hawkeyes and No. 2 Ohio State Buckeyes. Both teams are off a bye, and this is the first meeting since 2017 when Iowa crushed No. 3 Ohio State 55-24 as an 18-point home underdog.

Iowa vs Ohio State Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: IOWA: (+1400) | OSU: (-4000)
Spread: IOWA: +28.5 (-110) | OSU: -28.5 (-110)
Total: 49.5 — Over: (-106) | Under: (-114)

Ohio State is a huge -28.5 spread favorite and monster -4000 on the moneyline. An Iowa upset win would return +1400, or 14/1 times your moneyline bet. The betting line is up from the Sunday opener in Las Vegas of Ohio State -27, and the total is down 2 points from 51.5 to 49.5.

Iowa vs Ohio State Prediction & Pick

Iowa's offense ranks dead-last at No. 131 in FBS averaging 239 yards per game and 15 points per game ranks No. 127. Iowa QB's have been sacked 15 times the last four games. But the Hawkeyes' defense has been dominant, allowing just 10 points per game (PPG) to rank No. 3 in the country and their 265 yards per game (YPG) is top-10.

Ohio State is up to No. 2 in the AP Poll and one of two teams to average 300 passing yards and 200 rushing yards per game. Quarterback CJ Stroud (+100) is the Heisman favorite, and he's completing 71% of his passes for 1,737 yards and a 24:3 TD-INT ratio with loads of talented WRs and RBs. All American Jaxon Smith-Njigba (hamstring) is expected back this week after missing the last 3 games. The Buckeyes have won 27 straight home games dating back to 2015. Ohio State's defense has allowed just 16 PPG and 254 YPG.

Final Score Prediction: Ohio State: 37 | Iowa: 13

Iowa vs Ohio State Betting Trends

- Iowa is 0-7 straight up (SU) in their last 7 games at Ohio State.
- Iowa is 8-2 against the spread (ATS) in their last 10 road games.
- The total has hit the Under in 6 of Iowa's last 7 games.
- Ohio State is 7-0 SU in their last 7 games, and 27-0 in their last 10 home games.
- The total has hit the Over in 4 of Ohio State's last 5 games.

Iowa vs Ohio State Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

Tough to get behind Iowa with its impotent offense, but these lines are still through the roof as the bookmaker knows not many bettors will support the Hawkeyes, despite their top-tier defense.

Bet: Iowa +28.5 (-110)

Game odds refresh periodically and are subject to change.