Grizzlies vs Lakers Prediction, Odds & Best Bet for NBA Playoffs Game 6 (Can Los Angeles Eliminate Pesky Memphis?)

The 2022-23 NBA Playoffs continue on Friday, April 28 with Game 6 of the first-round series between the Memphis Grizzlies and Los Angeles Lakers.

Grizzlies vs Lakers Game 6 Info

• Series: LAL leads 3-2
• Date: Friday, April 28, 2023
• Time: 10:30 p.m. ET
• Venue: crypto.com Arena -- Los Angeles, California
• Coverage: ESPN

The Lakers failed on an opportunity to advance to the second round, losing 116-99 to the Grizzlies in Game 5. Desmond Bane and Ja Morant put on a show, recording 33 and 31 points, respectively, while collecting 10 rebounds apiece.

Grizzlies vs Lakers Odds & Spread

• All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.
• Moneyline: MEM: (+162) | LAL: (-194)
• Spread: MEM: +4.5 (-110) | LAL: -4.5 (-110)
• Total: 219.5 -- Over: (-110) | Under: (-110)

The Lakers enter this contest as clear home favorites on the moneyline and spread per FanDuel Sportsbook's odds. This 10:30 p.m. ET clash also features an over/under of 219.5 points with both sides available at -110 odds. 

Grizzlies vs Lakers Betting Trends

• Memphis is 2-4 straight up in its last six games.
• The Lakers are 5-0 straight up in their last five home games.
• Memphis is 3-7 against the spread (ATS) in its last 10 games.
• The Lakers are 4-1 ATS in their last five games played on a Friday.
• The total has hit the under in four of Memphis' last six games.
• The total has hit the under in 15 of the Lakers' last 20 games against Memphis.

Grizzlies vs Lakers Prediction & Pick

Two specific things stuck out about the Lakers' latest loss. For starters, LeBron James only scored 17 points on 5-of-17 shooting, so I expect him to get back on track at home. The second thing is that the Lakers' bench had a combined minus-97 plus/minus rating. The secondary unit is better than that, meaning that performance was more than likely an anomaly.

Fortunately for the Lakers, returning home should give them a boost. They've won five straight games at crypto.com Arena, including both against the Grizzlies thus far by an average margin of eight points. Speaking of which, Memphis is 1-8 straight up in its last nine trips to Los Angeles' home, losing in each of the previous four.

Check out more NBA Playoffs content from The Duel:

The Grizzlies' Game 4 effort was commendable, but it's clear that the bright lights of Los Angeles are too much to handle. Being 23-12 straight up as the favorite this season, look for the Lakers to finally close things out.

Final Score Prediction: Lakers: 117 | Grizzlies: 112

Grizzlies vs Lakers Best Bet

Backing the Lakers on the 4.5-point spread is the best bet for this game. Not only are they a respectable 4-1 ATS in their last five games on a Friday, but they're also 4-2 ATS in their last six encounters with the Grizzlies. Meanwhile, Memphis is 3-7 ATS in its last 10 outings while falling to cover in five of its previous six road games.

Considering how both of the Lakers' home wins this series came by at least six points, covering as the -4.5 favorite won't be an issue.

Bet: Lakers -4.5 (-110)

Watch FanDuel TV’s new NBA show “Run It Back” with Shams Charania, Michelle Beadle, Chandler Parsons, and Eddie Gonzalez Monday-Wednesday at 10 ET on FanDuel TV, the FanDuel Youtube page, or download the podcast here: fanduel.com/podcasts.

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.