Grizzlies vs. Lakers Prediction, Odds & Best Bet for NBA Playoffs Game 5 (Can LA Advance to the Second Round?)

The 2022-23 NBA Playoffs continue on Wednesday with Game 5 of the first round series between the Los Angeles Lakers and Memphis Grizzlies.

Grizzlies vs. Lakers Game Info

• Date: Wednesday, April 26, 2023
• Time: 7:30 PM ET
• Venue: FedExForum -- Memphis, Tennessee
• Coverage: TNT, BSSE, and SportsNet LA

The Lakers tied Game 4 at 104-104 thanks to a contested layup scored by LeBron James with under a second left to send the contest to overtime. That was when LA's experience took over as Memphis missed the shots it needed to make in order to keep up. LA eventually prevailed in a 117-111 thriller.

Grizzlies vs. Lakers Odds & Spread

• All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.
• Moneyline: MEM: (-174) | LAL: (+146)
• Spread: MEM: -4 (-110) | LAL: +4 (-110)
• Total: 221.5 -- Over: (-110) | Under: (-110)

The Grizzlies enter this contest as small favorites on the moneyline and spread per FanDuel Sportsbook's odds. This 7:30 p.m. ET clash also features an over/under of 221.5 points, with each side available at -110 odds.

Grizzlies vs Lakers Betting Information

Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Grizzlies	-4	-110	-110	221.5	-110	-110	-174	+146

Grizzlies vs. Lakers Betting Trends

• Memphis is 15-2 straight up in its last 17 home games.
• The total has hit the under in 15 of Memphis' last 20 games against the Lakers.
• The Lakers are 4-1 against the spread (ATS) in its last five games against Memphis.
• The total has hit the over in six of the Lakers' last seven away games.

Grizzlies vs. Lakers Prediction & Pick

Game 4 was nothing short of a back-breaking loss for Memphis. Jaren Jackson Jr. pulled off a clutch block and it led to a Desmond Bane layup with under seven seconds to go, but the Grizzlies couldn't get the job done. They will now have to win each of the final three games in this series to advance.

Memphis has a clear opportunity to check off the first of those three wins on Wednesday. This series shifts back to FedEx Forum, where the Grizzlies have posted a 36-7 record this season as well as a +10.0 average scoring margin (No. 3 in NBA). They also rank second in home defensive efficiency.

Picking against one of the greatest players of all-time is never easy, especially given James' career playoff stats on the road mirror his stats at home. The Lakers have lost four of their last five away games against the Grizzlies, though, and rank 25th in road scoring defense (118.8 points per game).

Final Score Prediction: Grizzlies: 114 | Lakers: 109

Grizzlies vs. Lakers Best Bet

I like the Grizzlies' chances of squeaking out a win on Wednesday night, but I don't like their chances of putting together a blowout victory. Memphis lost Game 1 at home and only won by 10 points in Game 2 despite controlling the game from start to finish. The Lakers just know how to stick around.

Keep in mind the Lakers own a 7-3 record across their last 10 away games and all three of those losses came by a margin of less than 11 points. James is leading a squad full of underrated shooters and will give Memphis a run for its money on Wednesday. I just see the Lakers coming up short.

Bet: Win Margin - Memphis Grizzlies 1-10 (+175)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.