Giants vs Cowboys Prediction, Odds & Best Bet for Week 12 Thanksgiving Game (Dallas Dominates NFC East Clash)

Giants vs Cowboys Week 12 Game Info

2022 NFL Regular Season Game
New York Giants (7-3, 3-1 Away) vs. Dallas Cowboys (7-3, 4-1 Home)
Date: Thursday, Nov. 24, 2022
Time: 4:30 p.m. ET
Venue: Ford Field — Detroit, MI
Coverage: CBS

Week 12 of the 2022 NFL season includes a Thanksgiving showdown between the New York Giants and Dallas Cowboys. Despite one of the hotter starts to the campaign, the Giants have now lost two of their last three games, including a 31-18 loss to the Detroit Lions on Sunday.

At the same time, momentum is as high as can be for the Cowboys. Mike McCarthy's squad responded to a Week 10 loss with a 40-3 blowout win over the Minnesota Vikings this past weekend. Dallas running back Tony Pollard couldn't be contained in the win, picking up 189 yards from scrimmage and two touchdowns on 21 touches (15 carries, six catches).

Giants vs Cowboys Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: NYG: (+315) | DAL: (+400)
Spread: NYG: +8.5 (-114) | DAL: -8.5 (-106)
Total: 44.5 —Over: (-112) | Under: (-108)

The Cowboys enter this contest as heavy favorites on the moneyline and spread on FanDuel Sportsbook's updated odds. This Thanksgiving clash also features an over/under of 44.5, which is about average compared to the Week 12 totals. 

Giants vs Cowboys Prediction & Pick

This matchup is the second between these NFC East rivals this season. The Cowboys already defeated the Giants, 23-16, back in Week 3 with Cooper Rush under center, giving the former their 10 victories in the last 11 meetings with their division rivals.

Being held to 18 or fewer points by teams like the Lions and Seattle Seahawks over their last three outings, I don't believe that the Giants will get much going against the Cowboys. On top of having the NFL's No. 1 defense, Dallas has recorded 16 takeaways in 2022 (No. 7) and is looking forward to taking on a New York team that's coughed the ball up five times in its last three games.

With the Giants also having not won at AT&T Stadium since September 2016, going 0-5 straight up since then, I'm backing the Cowboys to feast this Thanksgiving.

Final Score Prediction: Cowboys: 35 | Giants: 20

Giants vs Cowboys Betting Trends

- The Giants are 1-8 straight up in their last nine road games against Dallas.
- Dallas is 7-2 against the spread (ATS) in its last nine games.
- The total has hit the under in four of the Giants' last five games.
- The total has hit the over in six of Dallas' last eight games against the Giants.

Giants vs Cowboys Best Bet

After the Cowboys beat the Vikings by 37 points last week, I don't think the Giants have much of a chance here. New York is an uninspiring 2-9 against the spread (ATS) in its last 11 games against Dallas, which is 4-1 ATS at home so far. With the Giants also looking like pretenders in recent weeks, I see the Cowboys putting their rivals in their place by covering the 8.5-point spread.

Bet: Cowboys -8.5 (-106)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.