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Florida State vs LSU Prediction, Odds & Betting Trends for College Football Game on FanDuel Sportsbook (Sept 4)

Larry Rupp
Florida State vs LSU prediction, odds and betting trends for NCAA college football game.
Florida State vs LSU prediction, odds and betting trends for NCAA college football game. / AP Photos/Gerald Herbert
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Florida State vs LSU Week 1 Game Info

2022 NCAA College Football Game
Florida State Seminoles (1-0) vs. LSU Tigers (0-0)
Date: Sunday, September 4, 2022
Time: 7:30 p.m. ET
Venue: Caesars Superdome — New Orleans, LA
Coverage: ABC

Week 1 of the 2022 NCAA college football season includes a showdown between the Florida State Seminoles and LSU Tigers in the Allstate Louisiana Kickoff. This will be LSU's first game under new head coach Brian Kelly, who has yet to reveal the Tigers starting quarterback for Sunday night.

Meanwhile, Florida State go their season started in August by taking down Duquesne by a score of 47-7. The Seminoles are in the midst of four straight losing seasons, though, so the pressure is on head coach Mike Norvell to turn things around. Grabbing a win here would be the perfect first step.

Florida State vs LSU Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: FSU: (+128) | LSU: (-154)
Spread: FSU: +3.5 (-124) | LSU: -3.5 (+102)
Total: 50.5 — Over: (-110) | Under: (-110)

LSU enters this contest as the small favorite on the moneyline and the spread. This 7:30 p.m. ET clash also features a total of 50.5, which is below average compared to this week's college football projected totals.

Florida State vs LSU Prediction & Pick

Don't be surprised if this game comes down to the fourth quarter or even the final drive. These teams stack up well, but keep in mind this is essentially a home game for the Tigers. If QB Jayden Daniels is named the starter, his mobility could keep Florida State's defense guessing from play to play as well.

One key matchup sticks out in this game. The Seminoles had three players rush for over 100 yards and average over nine yards per carry last week. On the other side, LSU's linebacker core doesn't have a household name yet. Look for someone to step up when it matters the most and shut FSU down.

Final Score Prediction: Florida State: 24 | LSU: 28

Florida State vs LSU Betting Trends

- Florida State is 1-4 straight up in its last five games against a SEC opponent.
- The total has hit the over in six of Florida State's last eight Week 1 games.
- LSU is 11-2 straight up in its last 13 games in September.
- The total has hit the over in 11 of LSU's last 13 Week 1 games.

Florida State vs LSU Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

A loss out of the gate for Kelly would be a disastrous start to his head coaching tenure. He knows that the country is looking for him to get the Tigers back to the College Football Playoffs sooner than later. The good news is that LSU has dominated the ACC, winning its last five games against the conference.

Florida State is just 1-4 in its last five matchups against the SEC conference. The Seminoles allowed 232.4 passing yards per game in 2021 (No. 70 in FBS) and now have to face the nation's best wide receiver in Keyshone Boutte. Look for him to be the difference-maker and help LSU cover the spread.

Bet: LSU -3.5 (+102)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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