Eagles vs Lions Opening Odds Show Clear Favorite in Week 1 on FanDuel Sportsbook

The NFL was able to garner more excitement for the 2022 season by releasing entire schedules for each of the 32 franchises on Thursday night. Fans are now digging deep into every matchup and trying to determine whether or not their favorite team has a real shot at winning the Super Bowl.

Eagles vs Lions Week 1 Odds

The good news is FanDuel Sportsbook has already posted opening lines for each Week 1 NFL game. With plenty of great games on the slate in Week 1, the Philadelphia Eagles traveling to take on the Detroit Lions definitely sticks out as one to watch.

Eagles vs Lions Opening Odds

According to FanDuel Sportsbook's NFL odds, the Eagles head into Ford Field as 4.5-point favorites over the hometown Lions, with odds set at -110 for either team to cover the spread. Philadelphia also holds -205 moneyline odds, while Detroit is +172 to pull off an early season upset.

Keep in mind these two teams did meet in 2021 as running backs Boston Scott and Jordan Howard tallied two rushing touchdowns each during the Eagles' 44-6 blowout victory. The Lions were held to only 57 yards on the ground on 18 carries and saw numerous drives end after only a few plays.

This will be a huge game for debuts as first round pick Aidan Hutchinson will be suiting up along the Detroit defensive line. Meanwhile, Eagles fans will get their first look at trade acquisition AJ Brown. The Pro Bowl wide receiver has racked up 2,995 yards and 24 touchdowns across three NFL seasons.

A simple look at the Super Bowl odds shows just how much of a mismatch this Week 1 game could end up being. FanDuel Sportsbook has the Eagles slated at +3500 odds (No. 16) to win Super Bowl LVII in February, whereas the Lions check in at +10000 odds (T-No. 25).

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.