Eagles vs Cardinals Opening Odds, Betting Lines & Prediction for Week 5 Game on FanDuel Sportsbook

Week 4 NFL action is underway, but FanDuel Sportsbook has already released NFL odds and lines for Week 5, giving us an early preview of next week's slate.

Week 5's late slate sets up an exciting NFC matchup between the Philadelphia Eagles and Arizona Cardinals.

Eagles vs Cardinals Odds & Lines Week 5

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: PHI: (-215) | ARI: (+180)
Spread: PHI: -3.5 (-115) | ARI: +3.5 (-105)
Total: N/A — Over: (N/A) | Under: (N/A)

The undefeated Eagles are poised for a hard-fought game on the road in Week 5 against the Cardinals. Philadelphia is an early -215 moneyline favorite and is favored by 3.5 points on the spread.

Eagles vs Cardinals Prediction Week 5

Early NFL predictions and picks are from ESPN's Football Power Index (FPI).
Eagles: 54.2% to win
Cardinals: 45.2% to win

This is one of the few contests in Week 5 where the road team is favored by both the opening betting lines and ESPN's FPI. The Eagles are surrounded by high expectations, but I expect them to meet those expectations in a win. Philadelphia is not messing around this season as quarterback Jalen Hurts has himself in the early MVP conversation. He should have no trouble picking apart an Arizona secondary that ranks outside the top 20 NFL teams in pass-defense DVOA rating. Give me the Eagles -3.5 (-115).

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.