Duke vs Xavier Prediction, Odds & Best Bet for Nov. 25 (Blue Devils, Muskeeters Go Blow-for-Blow in Shootout)

Duke vs Xavier Game Info

2022-23 NCAA College Basketball Regular Season Game
No. 8 Duke Blue Devils (5-1) vs. Xavier Musketeers (4-1)
Date: Friday, Nov. 25, 2022
Time: 3:30 p.m. ET
Venue: Moda Center — Portland, OR
Coverage: ESPN

The 2022-23 NCAA college basketball season continues on Friday, Nov. 25 with a Phil Knight Legacy matchup between the No. 8 Duke Blue Devils and Xavier Musketeers.

Even though Duke couldn't get its offense going against Oregon State on Thursday, the Blue Devils managed to stand strong and walk out with the 54-51 victory. Meanwhile, Xavier is riding high after coming out on the right side of a 90-83 shootout with Florida yesterday.

Can Duke find a way to get its top players going on Friday? Or will Xavier find a way to keep its momentum going to get to the next stage of the Phil Knight Legacy tournament?

Duke vs Xavier Odds & Spread

All NCAA college basketball betting lines, odds and prop bets.
Moneyline: DUKE: (-200) | XAV: (+164)
Spread: DUKE: -4.5 (-110) | XAV: +4.5 (-110)
Total: 146.5 —Over: (-115) | Under: (-105)

Duke enters this contest as the clear favorite on the moneyline and spread per FanDuel Sportsbook's odds. This 3:30 p.m. ET clash also features an over/under of 146.5 points, which is higher than most of Friday's projected totals.

Duke vs Xavier Prediction & Pick

Not only did Duke look quite vulnerable against Oregon State, but the former looked downright terrible at times. The Blue Devils just couldn't hit their shots when they needed to the most, shooting 26.7% from the floor and 17.2% from three-point range.

Having said that, I do expect Duke to find its groove against Xavier. The Musketeers' defense is nothing special and allows a lot of opportunities, sitting bottom-30 in the nation when it comes to field-goal attempts allowed while giving up 27.2 makes per game (No. 256).

Even after yesterday's low-scoring outing, Duke is still averaging 73.2 PPG. I trust that Jon Scheyer will get his team back on track to take advantage of Xavier's defense, leading to a Blue Devils victory.

Final Score Prediction: Duke: 79 | Xavier: 74

Duke vs Xavier Betting Trends

- Duke is 5-0 straight up in its last five games as the favorite.
- Xavier is 5-0-1 against the spread (ATS) in its last six games played on Friday.
- The total has hit the over in 12 of Duke's last 13 games against the Big East.
- The total has hit the over in each of Xavier's last eight games.

Duke vs Xavier Best Bet

This game has all the makings of a shootout. Along with Duke's solid offense, Xavier is averaging the 14th-most points (85.8 PPG) in college basketball. Together, the two sides combine for 159 PPG.

With the total going over in each of the Musketeers' last eight games, as well as in 12 of the Blue Devil's most recent 13 against the Big East, give me the total going over 146.5 points this afternoon.

Bet: Over 146.5 Points (-115)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.