Colts vs Vikings Prediction, Odds & Best Bets for Week 15 (Minnesota Bounces Back at U.S. Bank Stadium)

Larry Rupp
Indianapolis Colts vs Minnesota Vikings prediction, odds and best bets for NFL Week 15 game.
Indianapolis Colts vs Minnesota Vikings prediction, odds and best bets for NFL Week 15 game. / AP Photos/Paul Sancya
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Colts vs Vikings Week 15 Game Info

2022 NFL Regular Season — Week 15
Indianapolis Colts (4-8-1, 2-4-1 Away) vs. Minnesota Vikings (10-3, 6-1 Home)
Date: Saturday, Dec. 17, 2022
Time: 1:00 p.m. ET
Venue: U.S. Bank Stadium — Minneapolis, MN
Coverage: NFL Network

The Minnesota Vikings will look to stay in the hunt for the NFC's No. 1 seed when they host the Indianapolis Colts in Week 15. The Colts were crushed, 54-19, by the Dallas Cowboys in their most recent game in Week 13. Head coach Jeff Saturday is hoping the bye week has helped in preparation.

Meanwhile, the Vikings couldn't keep up in a 34-23 loss to the Detroit Lions on Sunday. Minnesota's defense was torched again as quarterback Jared Goff logged 330 yards and 3 touchdowns. A stellar performance by wide receiver Justin Jefferson (11 receptions, 223 yards) was simply put to waste.

Colts vs Vikings Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: IND: (+166) | MIN: (-198)
Spread: IND: +4 (-110) | MIN: -4 (-110)
Total: 48.5 — Over: (-110) | Under: (-110)

The Vikings enter this contest as notable home favorites on the moneyline and spread on FanDuel Sportsbook's odds. This Saturday clash also features one of the higher totals on the Week 15 slate at 48.5 points.

Colts vs Vikings Prediction & Pick

Momentum is not a word that can be associated with either one of these teams right now. The Colts were embarrassed in Dallas and the Vikings were picked apart in Detroit. Minnesota is in the perfect spot for a bounce-back win, though, considering it is 7-1 straight up in its last eight home games.

There's no denying that the Vikings' defense has been horrible, but the Colts' offense has been even worse. Indianapolis is averaging a measly 16.1 points (No. 31 in NFL) on 318.0 yards per game (No. 25 in NFL). Quarterback Matt Ryan's career-low mark of 9.9 yards per completion isn't helping one bit.

The Vikings are 5-2 straight up in their last seven home games against the Colts and I trust them to pull out a win in the end.

Final Score Prediction: Colts: 17 | Vikings: 30

Colts vs Vikings Betting Trends

- Indianapolis is 6-0 straight up in its last six games againt Minnesota.
- The total has hit the under in 14 of Indianapolis' last 18 games.
- Minnesota is 7-0 against the spread (ATS) in its last seven games against an AFC opponent.
- The total has hit the under in five of Minnesota's last six games against Indianapolis.

Colts vs Vikings Best Bet

While targeting the over is an intriguing option here, the Colts have scored more than 19 points just once over their last seven games. Trusting an offense that lacks reliable weapons to step up is a risky move. The Vikings don't lack those kind of weapons, which makes their team total the way to go.

Minnesota averages the eighth-most points per home game (25.3) and has tallied at least 27 points in seven of their last 11 games. The Colts have allowed an average of 177.7 rushing yards over their last three games (No. 28 in NFL), so look for running back Dalvin Cook to lead the Vikings to touchdowns.

Bet: Minnesota Vikings Total Points Over 26.5 (-116)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.

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