NCAAF Betting

California vs USC Prediction, Odds & Betting Trends for College Football Week 10 Game on FanDuel Sportsbook

Devon Platana
California vs. USC prediction, odds and betting trends for NCAA college football game.
California vs. USC prediction, odds and betting trends for NCAA college football game. / ASSOCIATED PRESS
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California vs USC Week 10 Game Info

2022 NCAA College Football Game
California Golden Bears (3-5, 1-4 Pac-12) vs. No. 9 USC Trojans (7-1, 5-1 Pac-12)
Date: Saturday, Nov. 5, 2022
Time: 10:30 p.m. ET
Venue: Los Angeles Memorial Coliseum — Los Angeles, CA
Coverage: ESPN

Week 10 of the 2022 NCAA college football season includes a Pac-12 rivalry matchup between the California Golden Bears and No. 9 USC Trojans. Things looked promising after California's 3-1 start to the year, only for the team to lose four straight games ahead of this matchup. The Golden Bears' most recent loss was an ugly one as they were blown out, 42-24, by then-No. 8 Oregon last week.

Meanwhile, USC got back on track after its first loss of the season, grabbing a 45-37 road win against Arizona in Week 9. Trojans quarterback Jayden de Laura and wideout Dorian Singer were an unstoppable force en route to the victory, connecting on seven passes for 141 yards and three touchdowns.

California vs USC Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: CAL: (+860) | USC: (-1600)
Spread: CAL: +21.5 (-110) | USC: -21.5 (-110)
Total: 60.5 — Over: (-114) | Under: (-106)

USC enters this contest as a clear home favorite on the spread and moneyline. This 10:30 p.m. ET clash also features a total of 60.5, which is high compared to this week's projected totals.

California vs USC Prediction & Pick

California's season has gone completely off the rails over the last month. The Golden Bears are now just 1-4 against the Pac-12 this fall and have been held to just 16.8 points over their current four-game losing skid. Any hope of relief is out the window in a road game against USC — the same team that only sits one game out of the conference's top spot due to the Week 7 loss to Utah.

The Trojans also have an attack that I don't think the Golden Bears can handle. USC is tied with Michigan for the sixth-best offense in the nation (41.0 PPG), also averaging an impressive 45.8 PG clip at home (fourth-best). That's not exactly promising for California, having gone 0-3 on the road thus far.

Another thing that makes this USC's game to lose is the program's recent success over its Pac-12 rival. The Trojans are 17-3 straight up in their last 20 games against the Golden Bears, which includes winning 14 consecutive games from 2004 to 2017. California may have won last year's meeting, 24-14, but all that does is give USC a bigger incentive to win this weekend.

Expect Cal's woes to continue as USC picks up yet another victory.

Final Score Prediction: USC: 45 | California: 23

California vs USC Betting Trends

- California is 1-10 straight up in its last 11 road games.
- USC is 11-5 against the spread (ATS) in its last 16 games against California.
- The total has hit the under in five of California's last seven games against the Pac-12.
- The total has hit the over in eight of USC's last 10 home games.

California vs USC Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

Although both schools are heading in opposite directions, I still think that a 21.5-point spread is a bit much. After all, California is a decent 4-4 against the spread this season, while USC has beaten the Golden Bears by 22-plus points just once in the last seven matchups.

I expect USC to win this one decisively, however, it'll be less than what the spread implies.

Bet: California +21.5 (-110)

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Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.

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