Bills vs Dolphins Prediction, Odds & Betting Trends for NFL Week 3 Game on FanDuel Sportsbook (Sept 25)

Buffalo Bills vs Miami Dolphins prediction, odds and betting trends for NFL Week 3 game.
Buffalo Bills vs Miami Dolphins prediction, odds and betting trends for NFL Week 3 game. / AP Photos/Adrian Kraus
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Bills vs Dolphins Week 3 Game Info

2022 NFL Regular Season — Week 3
Buffalo Bills (2-0, 1-0 Away) vs. Miami Dolphins (2-0, 1-0 Home)
Date: Sunday, September 25, 2022
Time: 1:00 p.m. ET
Venue: Hard Rock Stadium — Miami Gardens, FL
Coverage: CBS

Only six teams remain undefeated in the NFL and two go head-to-head in Week 3 as the Buffalo Bills visit the Miami Dolphins. The Bills have won each of their first two games by at least 21 points and crushed the Tennessee Titans by a score of 41-7 in Week 2. Quarterback Josh Allen is an early MVP favorite.

Meanwhile, the Dolphins mounted a furious comeback against the Baltimore Ravens in Week 2 to emerge victorious, 42-38. Quarterback Tua Tagovailoa tossed 6 touchdowns in the win and now leads the NFL with 739 passing yards in 2022. Facing the Bills' defense presents as a massive test, though.

Bills vs Dolphins Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: BUF: (-215) | MIA: (+180)
Spread: BUF: -4.5 (-110) | MIA: +4.5 (-110)
Total: 54 — Over: (-110) | Under: (-110)

Updated (Sunday, Sept. 25, 11:30 a.m. EST): Updated odds were provided from FanDuel Sportsbook. This line moved slightly in the Dolphins favor, down to just 4.5 points. The over/under also crept up by half a point to 54 points.

The Bills enter this contest as a clear favorite on the moneyline and the spread. This 1 p.m. ET clash also features one of the higher projected totals (53.5) on the NFL Week 3 slate.

Bills vs Dolphins Prediction & Pick

There's no denying that seeing the Dolphins jump to the top of the AFC East and cement themselves as an AFC contender with a win would be amazing. However, it's hard to pick against the Bills in any matchup. That's especially the case considering Buffalo is 7-0 in its last seven games against Miami.

This one will come down to whether or not the Dolphins' secondary can slow down wide receiver Stefon Diggs. The Pro Bowl talent has logged 270 yards and 4 touchdowns on 20 receptions through two games. His relentless energy will guide the Bills to a win, but it's not going to be a blowout win.

Final Score Prediction: Bills: 31 | Dolphins: 27

Bills vs Dolphins Betting Trends

- Buffalo is 7-0 straight up in its last seven games against Miami.
- The total has hit the over in 13 of Buffalo's last 19 away games.
- Miami is 9-2 against the spread (ATS) in its last 11 games.
- The total has hit the over in 10 of Miami's last 14 games against Buffalo.

Bills vs Dolphins Best Bet

All NFL betting lines, odds and prop bets are available on FanDuel Sportsbook.

This game has shootout written all over it. Both the Bills and Dolphins rank among the top five NFL teams in points per game, yards per game and yards per play through two weeks. Allen, Tagovailoa, Diggs, Tyreek Hill, Jaylen Waddle and Gabriel Davis headline two powerful passing attacks.

It's worth noting the over has hit in 10 of the last 14 head-to-head matchups between Buffalo and Miami. It has also hit in 13 of the Bills' last 19 away games and in seven of the Dolphins' last 10 Week 3 contests. Trust the trends here and back the over. Rooting for more points to be scored is exciting.

Bet: Over 53.5 Points (-106)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.