Arizona State vs USC Prediction, Odds & Betting Trends for College Football Game on FanDuel Sportsbook

Arizona State vs USC Week 5 Game Info

2022 NCAA College Football Game
Arizona State (1-3, 0-1 Pac12) vs. No. 6 USC Trojans (4-0, 2-0 Pac 12)
Date: Saturday, Oc. 1, 2022
Time: 10:30 p.m. ET
Venue: Memorial Coliseum — Los Angeles, CA
Coverage: ESPN

Week 5 of the 2022 NCAA college football season features a Pac-12 mismatch between the Arizona State Sun Devils and No. 6 USC Trojans.

The undefeated Trojans (4-0) have been climbing up the AP rankings, and last week USC got their first big test and barely passed in a 17-14 win at tough challenger Oregon State.

Arizona State vs USC Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: ASU: (+1400) | USC: (-4000)
Spread: ASU: +25.5 (-112) | USC: -25.5 (-108)
Total: 60.5 — Over: (-105) | Under: (-115)

USC is a huge -25.5 point favorite and a monster on the moneyline at -4000. If ASU pulls the upset and wins, moneyline bettors are rewarded with 14/1 odds (+1400). The total is above average at 60.5 points with an expected blowout by the Trojans.

Arizona State vs USC Prediction & Pick

The Trojans may be able to name the score in this matchup, despite last week's 17-point output. The Trojans scored 66, 41 and 45 points in their three previous games, and rolled up more than 500 yards offense at Stanford in a 41-28 win when USC's defense was not as sharp. Arizona State can be run against and the Sun Devils lack a pass rush - a poor combination against an explosive offense with talented skill position players and a coach that likes to bury weaker opponents.

USC has yet to turn the ball over on offense, and the Trojans lead the nation in turnover margin at +14, and they will create more against Sun Devils QB Emory Jones.

Final Score Prediction: USC: 51 | ASU: 17

Arizona State vs USC Betting Trends

- Arizona State is 1-4 straight up (SU) in their last 5 games.
- Arizona State is 1-5 against the spread (ATS) in their last 6 road games
- The total has gone Under in ASU's last 5 games.
- USC is 4-1 SU in their last 5 games.
- USC is 4-2 ATS in their last 6 games.
- The total has gone Over in 7 of USC's last 8 home games.

Arizona State vs USC Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

First-year Trojans coach Lincoln Riley is enjoying LA and his team can roll to another big win with their capable explosive top-rated offensive attack led by Heisman contending QB Caleb William. The Trojans defense had 4 interceptions last week, and Sun Devils QB Emery Jones tossed two INT's last week and is going to be pressured, battered and beaten again this Saturday.

Bet: USC -25.5 (-25.5)