76ers vs. Celtics Prediction, Odds & Best Bet for NBA Playoffs Game 1 (Boston Wins Series Opener at Home)

The 2022-23 NBA Playoffs continue on Monday with Game 1 of the Eastern Conference Semifinals between the Philadelphia 76ers and Boston Celtics.

Which conference rival will open the series with a win? Let's explore.

76ers vs. Celtics Game Info

• Date: Monday, May 1, 2023
• Time: 7:30 p.m. ET
• Venue: TD Garden -- Boston, Massachusetts
• Coverage: TNT

The Celtics and 76ers will resume their rivalry in Boston on Monday night at TD Garden. Boston is fresh off downing the Atlanta Hawks in six games, while Philly has had plenty of time to rest after sweeping the Brooklyn Nets.

After winning the regular-season series 3-1, can the Celtics continue their success against the Sixers?

76ers vs. Celtics Odds & Spread

• All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.
• Moneyline: PHI: (+240) | BOS: (-295)
• Spread: PHI: +7.5 (-112) | BOS: -7.5 (-108)
• Total: 215 -- Over: (-110) | Under: (-110)

The Celtics enter Game 1 as significant home favorites on the spread and moneyline at FanDuel Sportsbook. Monday's matchup also features a total of 215 points, which is on the lower side for an NBA game.

76ers vs. Celtics Betting Trends

• Boston is 34-10 straight up at home this season.
• Philadelphia is 27-16 straight up on the road this season.
• The Celtics are 8-2 against the spread in their last 10 games.
• The 76ers are 6-3-1 against the spread in their last 10 games.

76ers vs. Celtics Prediction & Pick

The 76ers haven't played since beating the Nets on April 22. After more than a full week off, they'll be well-rested but also perhaps a bit rusty.

They'll also have to travel to TD Garden, where the Celtics have a .773 winning percentage this year. Philly lost both of its regular-season trips to Boston by a combined 16 points.

Furthermore, there are reasons to doubt the Sixers. James Harden has been notoriously hit-or-miss throughout his playoff career, and Joel Embiid has a tough matchup against Celtics big man Robert Williams III.

Meanwhile, Jayson Tatum and Jaylen Brown are both coming in hot after torching the Hawks in the first round. Philly will keep things close with its elite defense, but Boston's superior firepower should prevail.

Final Score Prediction: Celtics: 110 | 76ers: 104

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76ers vs. Celtics Best Bet

Fans and sports bettors should expect a lower-scoring Game 1 for a few reasons. For starters, the 76ers may be a bit sluggish after their extended layoff and could take some time to find their rhythm on offense.

Second, both of these teams are among the top defensive units in the NBA. Philadelphia allowed the third-fewest points per game during the regular season while Boston yielded the fifth. Both teams also ranked bottom-11 in pace, so buckets could be at a premium in this game.

With the last three meetings between these two teams averaging just 208.7 points, taking the Under is the way to go in Game 1.

Bet: Under 215 Total Points (-110)

Game odds refresh periodically and are subject to change.