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49ers vs Broncos Opening Odds, Betting Lines & Prediction for Week 3 Sunday Night Football on FanDuel

Adam Taylor McKillop
49ers vs Broncos NFL opening odds, lines and predictions for Week 3 Sunday Night Football matchup.
49ers vs Broncos NFL opening odds, lines and predictions for Week 3 Sunday Night Football matchup. / ASSOCIATED PRESS
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Week 2 NFL action is underway, but FanDuel Sportsbook has already released NFL odds and lines for Week 3, giving us an early preview of next week's slate.

Week 3's Sunday Night Football sets up an exciting matchup between the San Francisco 49ers and Denver Broncos.

49ers vs Broncos Odds & Lines Week 3

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SF: (+128) | DEN: (-152)
Spread: SF: +2.5 (-102) | DEN: -2.5 (+120)
Total: N/A — Over: (N/A) | Under: (N/A)

The Broncos are poised for a hard-fought victory in Week 3 against the 49ers. Denver is considered -152 moneyline favorites, and by 2.5 points on the spread.

49ers vs Broncos Prediction Week 3

Early NFL predictions and picks are from ESPN's Football Power Index (FPI).
49ers: 40.2% to win
Broncos: 59.3% to win

Even while playing at home, Russell Wilson and the Denver Broncos are not considered big favorites in this matchup. It should be a good defensive battle, and bettors will want to take advantage of the favorable +120 odds on Denver's 2.5-point spread. Wilson and his team should perform well at home. Bet Broncos -2.5 (+120).

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Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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