49ers Playoff Chances, Odds & Prediction for 2022 NFL Season

Larry Rupp
San Francisco 49ers playoff chances, odds & a record prediction for the 2022 NFL season.
San Francisco 49ers playoff chances, odds & a record prediction for the 2022 NFL season. / Gary A. Vasquez-USA TODAY Sports
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The San Francisco 49ers have silenced the doubters over the last three seasons with two NFC Championship game appearances. It's become clear that this is a roster capable of beating any team in the league when it is firing on all cylinders, but whether or not it will be in 2022 remains to be seen.

Head coach Kyle Shanahan has been adamant that the time is now for quarterback Trey Lance to take over the starting gig from veteran Jimmy Garoppolo. The 2021 No. 3 overall pick will look to guide his team to the postseason after accounting for 6 touchdowns during his rookie year.

Let's break down the 49ers' playoff chances in 2022 using odds provided by FanDuel Sportsbook.

49ers Playoff Chances 2022

San Francisco is available at -220 to make the postseason. That equates to an implied probability of 68.8% for the 49ers to earn a playoff berth.

San Francisco 49ers Playoff Odds 2022

The 49ers head into the 2022 season with the second-best odds to win the NFC West. The Los Angeles Rams remain the favorite at +130, but San Francisco is right on their tail at +190. The Arizona Cardinals (+700) and Seattle Seahawks (+1300) remain long shots to earn a division title.

49ers 2022 Schedule

  • Week 1: @ Chicago Bears
  • Week 2: vs Seattle Seahawks
  • Weeks 3: @ Denver Broncos
  • Week 4: vs. Los Angeles Rams
  • Week 5: @ Carolina Panthers
  • Week 6: @ Atlanta Falcons
  • Week 7: vs Kansas City Chiefs
  • Week 8: @ Los Angeles Rams
  • Week 9: BYE
  • Week 10: vs Los Angeles Chargers
  • Week 11: vs Arizona Cardinals
  • Week 12: vs New Orleans Saints
  • Week 13: vs Miami Dolphins
  • Week 14: vs Tampa Bay Buccaneers
  • Week 15: @ Seattle Seahawks
  • Week 16: vs Washington Commanders
  • Week 17: @ Las Vegas Raiders
  • Week 18: vs Arizona Cardinals

49ers Win Total Over/Under 2022

The 49ers' win total has been set at 9.5 with -145 odds on the over and +125 odds on the under.

49ers Odds to Win AFC 2022

San Francisco is not being overlooked by oddsmakers as a contender to represent the NFC in the Super Bowl. The 49ers own the fourth-best odds to win the NFC outright at +750. That ranks ahead of the Dallas Cowboys (+850) and close behind last year's NFC champion, the Los Angeles Rams (+500).

49ers Super Bowl Odds 2022

As for the Lombardi Trophy, Shanahan's team is available at +1600 to win it all. Those odds rank tied for sixth with the Los Angeles Chargers among all NFL franchises. Keep in mind San Francisco checks in ahead of notable teams such as the reigning AFC champion Cincinnati Bengals (+2200).

49ers 2022 Season Prediction

The 49ers are balanced on both sides of the football. San Francisco has finished as a top-15 team in total yards per game in each of the last three seasons and posted the seventh-best total DVOA rating in the NFL last year. Big names like Nick Bosa and George Kittle are used to playing in the spotlight.

That's going to come in handy when facing top-tier competition. The 49ers go through a midseason gauntlet that features seven straight games against teams that posted a winning record in 2021. That's their best opportunity to showcase they are not a team to be underestimated any longer.

San Francisco is a ridiculous 18-7 on the road during the past three regular seasons and the athletic upside of Lance makes their ceiling even higher moving forward. The 49ers are in perfect position to lock down a Wild Card spot and could battle LA for NFC West supremacy if all goes well.

49ers 2022 Record Prediction: 11-6

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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