NFL - Odds & Predictions

49ers vs Cowboys Prediction, Odds, Spread, Over/Under & Betting Trends for NFL NFC Wild Card Game on FanDuel

Devon Platana
San Francisco 49ers vs Dallas Cowboys prediction, odds, spread, over/under and betting trends for NFL NFC Wild Card game.
San Francisco 49ers vs Dallas Cowboys prediction, odds, spread, over/under and betting trends for NFL NFC Wild Card game. / Tom Pennington/GettyImages
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49ers vs Cowboys Wild Card Game Info

NFL Playoffs — Wild Card Round
San Francisco 49ers (10-7, 6-3 Away) vs. Dallas Cowboys (12-5, 5-3 Home)
Date: Sunday, January 16, 2022
Time: 4:30 p.m. EST
Venue: AT&T Stadium — Arlington, TX
Coverage: CBS

49ers vs Cowboys Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SF: (+136) | DAL: (-162)
Spread: SF: +3 (-108) | DAL: -3 (-112)
Total: 51 — Over: (-106) | Under: (-114)
Odds to Win Super Bowl LVI: SF: (+2100) | DAL: (+1200)

49ers vs Cowboys Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: Dallas Cowboys win (66.3%)

49ers vs Cowboys Betting Trends

- San Francisco is 4-1 against the spread (ATS) in its last five games.
- Dallas is 4-1-1 ATS in its last six games against San Francisco.
- The total has hit the over in seven of San Francisco's last eight road games against Dallas.
- The total has hit the over in eight of Dallas' last 11 home games.


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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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