Southern Miss vs Miami Prediction, Odds, & Betting Trends for College Football Week 2 Game

Updated: Sep 10, 5:00pm UTC

Southern Miss vs Miami Week 2 Game Info

2022 NCAA College Football Game
Southern Miss Golden Eagles (0-1, 0-0) vs. Miami Hurricanes (1-0, 0-0)
Date: Saturday, Sept. 10, 2022
Time: 12:00 p.m. ET
Venue: Hard Rock Stadium — Coral Gables, FL
Coverage: ACC Network

College football's early Saturday schedule includes the Southern Miss Golden Eagles taking on the No. 15 Miami Hurricanes in their first ever meeting on Saturday, Sept. 10.

Southern Miss vs Miami Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: USM: (+1280) | MIA: (-3500)
Spread: USM: +24.5 (-105) | MIA: 24.5 (-115)
Total: 51.5 — Over: (-105) | Under: (-115)

Miami enters this contest as the huge favorite on the moneyline and the spread. This 12:00 p.m. ET clash also features a total of 51.5.

Southern Miss vs Miami Prediction & Pick

The Mario Cristobal era is off to a strong start after the Hurricanes score 70 last week vs Bethune-Cookman. Southern Miss lost in four overtimes to Liberty 29-27, and duel threat QB Ty Keyes is day-to-day after getting nailed in the chin and knocked out of the game in the second quarter.

Southern Miss turned to their Super Back Wildcat spinoff with star RB Frank Gore, Jr. They'll run the ball often if they can stay within range, but it will be difficult with Miami stacking the box and the Hurricanes balancing the offense with more passing this week. Miami does play at Texas A&M next week which is a lookahead situation that could prevent another big blowout.

Final Score Prediction: Miami 40 | Southern Miss: 13

Southern Miss vs Miami Betting Trends

Miami went 6-6-0 last season against the spread (ATS).
Miami has covered just 1 of their last 8 games as a home favorite vs FBS opponents.
Miami is 4-7 ATS vs non-conference foes since 2019.
Southern Miss games went over 57 points just one time last season.
Southern Miss is 2-4 ATS vs Power 5 teams since 2017.

Southern Miss vs Miami Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

The status of Southern Miss QB Ty Keys makes the Golden Eagles side and game total more speculative. But Miami will likely show more in the passing game this week and should roll early for bettors interested in first half wagering with less scoring in the second half.