Lions vs Vikings Prediction, Odds & Betting Trends for NFL Week 3 Game on FanDuel Sportsbook (Updated)

Lions vs Vikings Week 3 Game Info

2022 NFL Regular Season Game
Detroit Lions (1-1, 1-0 Away) vs. Minnesota Vikings (1-1, 1-0 Home)
Date: Sunday, Sept. 25, 2022
Time: 1 p.m. ET
Venue: U.S. Bank Stadium — Minneapolis, MN
Coverage: FOX

Week 3 of the 2022 NFL season includes an NFC North showdown between the Detroit Lions and Minnesota Vikings. The Lions hope to build their momentum following a 36-27 win over the Washington Commanders. Jared Goff put on a show with four touchdown passes while wideout Amon-Ra St. Brown had 184 total yards from scrimmage and two TDs.

On the flip side, a 24-7 loss to the Philadelphia Eagles on Monday has the Vikings looking to rebound. Minnesota just couldn't generate any offense, tallying only 264 total yards, which wasn't helped by the fact that Kirk Cousins handed out three interceptions.

Lions vs Vikings Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: DET: (+225) | MIN: (-275)
Spread: DET: +6.5 (-110) | MIN: -6.5 (-110)
Total: 51.5 —Over: (-114) | Under: (-106)

Updated (Sunday, Sept. 25, 11:30 a.m. EST): Updated odds were provided from FanDuel Sportsbook. The line continues to move in Minnesota's favor, with their point spread up to 6.5. The over/under total also fell two points down to 51.5.

The Vikings enter this contest as the favorite on the moneyline and spread on FanDuel Sportsbook's updated odds. This 1 p.m. ET clash also features a total of 53.5, which is tied for the highest Week 3 projected total.

Lions vs Vikings Prediction & Pick

While the Vikings have dominated this rivalry lately, it was actually the Lions who won their last game, 29-27, against their NFC North rival in Week 13 of 2021. With Detroit being a much better team this season, I like the Lions' odds of pulling off a road upset this week.

Even with the Vikings having a superstar like Justin Jefferson on offense, Cousins looked putrid on Monday. Detroit's pass rush has been solid this season and with its offensive line looking great on the other side of the ball, I see the Lions surprising a lot of people with their next performance.

Final Score Prediction: Lions: 27 | Vikings: 24

Lions vs Vikings Betting Trends

- Detroit is 7-1 against the spread (ATS) in its last eight games against the NFC.
- Minnesota is 2-7 straight up in its last nine games played in September.
- The total has hit the over in four of Detroit's last five games.
- The total has hit the under in eight of Minnesota's last nine home games against Detroit.

Lions vs Vikings Best Bet

The Lions play with a ton of heart under Dan Campbell and are capable of pulling off an upset on any given night. Momentum is on Detroit's side entering Week 2 and with Minnesota looking questionable at best after its last loss, back the Lions as +200 underdogs on the moneyline.

Bet: Lions ML (+200)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.