Eagles vs Cowboys Prediction, Odds & Best Bets for Week 16 (NFC East Battle Goes Down to the Wire in Dallas)

Eagles vs Cowboys Prediction, Odds & Best Bets for Week 16 (NFC East Battle Goes Down to the Wire in Dallas)


Eagles vs Cowboys Week 16 Game Info

2022 NFL Regular Season — Week 16
Philadelphia Eagles (13-1, 7-0 Away) vs. Dallas Cowboys (10-4, 7-1 Home)
Date: Saturday, Dec. 24, 2022
Time: 4:25 p.m. ET
Venue: AT&T Stadium — Arlington, TX
Coverage: FOX

The Philadelphia Eagles will attempt to stay unbeaten on the road this season when they travel to take on the Dallas Cowboys in Week 16 NFL action. The Eagles defeated the Chicago Bears, 25-20, on Sunday thanks to quarterback Jalen Hurts. The third-year pro tallied 3 more rushing touchdowns.

Meanwhile, the Cowboys fell short in a 40-34 overtime loss to the Jacksonville Jaguars in Week 15. Dallas held a 17-point lead late in the third quarter before it fell apart on defense. Quarterback Dak Prescott logged 256 yards and 3 touchdowns on the day, but also threw a pair of costly interceptions.

Eagles vs Cowboys Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: PHI: (+188) | DAL: (-225)
Spread: PHI: +5.5 (-118) | DAL: -5.5 (-104)
Total: 46 — Over: (-110) | Under: (-110)

The Cowboys enter this contest as notable home favorites on the moneyline and spread on FanDuel Sportsbook's odds. This 4:25 p.m. ET clash also features one of the higher totals on the Week 16 slate at 46 points.

Eagles vs Cowboys Prediction & Pick

Of course, it has to be mentioned right away that Hurts may not play in this game due to a sprained shoulder. The MVP candidate has been the force behind Philadelphia's offense all year long and his absence would cause Gardner Minshew to start. Nothing has officially been announced yet, though.

Dallas already ranks second in the NFL with 49.0 sacks this season and could bring a ton of pressure if it is Minshew in the pocket. The Cowboys have also posted the best pass defense DVOA rating in the NFL and have logged 12 interceptions as well. This is not the defense a backup QB wants to face.

The Cowboys will be aiming to avoid a season sweep against a divisional rival and are 7-3 straight up in their last 10 games against the Eagles. They do just enough to squeak out a victory at home.

Final Score Prediction: Eagles: 21 | Cowboys: 24

Eagles vs Cowboys Betting Trends

- Philadelphia is 3-7 straight up in its last 10 games against Dallas.
- The total has hit the over in seven of Philadelphia's last nine games.
- Dallas is 5-1 against the spread (ATS) in its last six home games against Philadelphia.
- The total has hit the over in four of Dallas' last five games against Philadelphia.

Eagles vs Cowboys Best Bet

This spread opened at 1-point in favor of the Cowboys following Week 15 action before jumping all the way up to the 5.5-point mark it is at now. That solely has to do with Hurt's health. It's important to keep in mind Philly is much more than a QB, though. This team is absolutely loaded with weapons.

Miles Sanders, AJ Brown and DeVonta Smith each scored a touchdown against the Cowboys back in Week 6. They are all healthy and ready to pounce. The Cowboys are also 2-4 against the spread (ATS) in their last six games and 1-5-1 ATS in their last seven Saturday home games, so give me the points.

Bet: Philadelphia Eagles +5.5 (-118)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.