Diamondbacks vs Phillies Prediction, Odds & Best Bet for May 22 (Back a Low-Scoring Contest in Philadelphia)

Diamondbacks vs Phillies Prediction, Odds & Best Bet for May 22 (Back a Low-Scoring Contest in Philadelphia)


The Philadelphia Phillies (22-24) will attempt to climb closer to the .500 mark when they host the Arizona Diamondbacks (27-20) in the first matchup of their three-game series on Monday, May 22.

Diamondbacks vs Phillies Game Info

  • Date: Monday, May 22, 2023
  • Time: 6:40 p.m. ET
  • Venue: Citizens Bank Park -- Philadelphia, PA
  • Coverage: BSAZ and NBCSP

It's been a shaky start to the year for the defending NL champions, but the Phillies are coming off a series in which they took two of three games against the Chicago Cubs. Meanwhile, Arizona has exceeded expectations so far and travels to Philly fresh off a series win over the Pittsburgh Pirates.

Diamondbacks vs Phillies Odds & Spread

  • All MLB betting lines, odds and prop bets are from FanDuel Sportsbook.
  • Moneyline: ARI: (+194) | PHI: (-235)
  • Spread: ARI: +1.5 (-110) | PHI: -1.5 (-110)
  • Total: 9 -- Over: (+100) | Under: (-122)

The Phillies enter this contest as home favorites on the moneyline and spread per FanDuel Sportsbook's odds. This 6:40 p.m. ET clash also features an over/under of 9 runs with the under favored at -122 odds.

Diamondbacks vs Phillies Betting Trends

  • Arizona is 3-6 straight up in its last nine games against Philadelphia.
  • The total has hit the over in 10 of Arizona's last 14 away games.
  • Philadelphia is 5-1 straight up in its last six home games.
  • The total has hit the over in six of Philadelphia's last seven games against Arizona.

Diamondbacks vs Phillies Prediction & Pick

The Diamondbacks will look to pull off an upset on Monday with Tommy Henry on the mound. The 25-year-old has made five starts for Arizona this season, posting a 5.00 ERA and 1.48 WHIP across 27.0 innings. He has struggled with command given he has allowed at least 2 walks in four of five starts.

The same thing cannot be said about Phillies' starter Zack Wheeler, though. Wheeler has only walked a total of three batters over his last four starts. The All-Star hurler has logged 27 strikeouts over that same span, too. Wheelers enters Monday night looking to improve his 4.06 ERA in the 2022 season.

Playing the Phillies at Citizens Bank Park is not something any MLB team should want to do. After all, the Dodgers are the only National League squad with fewer home losses (7) than the Phillies (8). Look for a Philadelphia bullpen that posted a 3.65 ERA in its last series to shut things down late in this one.

Final Score Prediction: Diamondbacks: 3 | Phillies: 4

Diamondbacks vs Phillies Best Bet

This game has low-scoring battle written all over it. On one side, Wheeler owns a 2.95 ERA across nine career starts against Arizona. On the other side, the Phillies have posted the seventh-worst batting average against left-handed pitching this year (.234). It's worth noting the total has hit the under in six of the Diamondbacks' last nine games against an NL East opponent. Back that trend to continue here.

Bet: Under 9 Total Runs (-122)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.