Colts vs Broncos Expert Picks & Predictions for Week 5 NFL Thursday Night Football Game

The 2022 NFL season is finally here and the Week 5 schedule is chock full of exciting showdowns. The action kicks off with a Thursday Night Football battle between AFC teams as the Indianapolis Colts visit the Denver Broncos.

The Colts' disappointing start to the season continued last week with a 24-17 loss to the Tennessee Titans. Meanwhile, the Broncos are also hoping to bounce back after losing, 32-23, to the rival Las Vegas Raiders.

Can the Jonathan Taylor-less Colts pull off a Thursday night miracle? Or will the Broncos use their opponents' injuries as a means to propel themselves to victory?

Here's what projection models and experts across the industry have to say about the Colts vs Broncos Week 5 matchup.

Colts vs Broncos Projections

ESPN FPI: Broncos (59.9%)
numberFire: Broncos (61.2%)
FiveThirtyEight: Broncos (60%)
Betting Favorite: Broncos (-3.5)

Projected Winner: Broncos (4)

Colts vs Broncos Expert Picks

ESPN Experts: Broncos (6), Colts (1)
CBS Sports Experts: Broncos (5), Colts (2)

Expert Totals: Broncos (11), Colts (3)

When it comes to projections, all four of the highlighted source sare backing the Broncos to win. While the experts' assessment isn't unanimous, 78.5% of them also side with a Denver victory.

As far as a Colts upset goes, their best shot at winning comes in at 40.1% on ESPN, which isn't much to write home about.

Even though the Broncos have been disappointing so far, all signs point to a Denver victory as the Colts try to figure out how to overcome Taylor's absence.

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.