Broncos vs Bills Prediction, Odds & Betting Trends for NFL Preseason Game on FanDuel Sportsbook (Aug 20)

Broncos vs Bills Prediction, Odds & Betting Trends for NFL Preseason Game on FanDuel Sportsbook (Aug 20)


Broncos vs Bills Preseason Game Info

2022 NFL Preseason Game
Denver Broncos (1-0) vs. Buffalo Bills (1-0)
Date: Saturday, August 20, 2022
Time: 1:00 p.m. ET
Venue: Highmark Stadium — Orchard Park, NY
Coverage: NFL Network

The Denver Broncos and Buffalo Bills meet head-to-head in NFL preseason action on Saturday. Denver is riding high after defeating the Dallas Cowboys by a score of 17-7 last weekend. Quarterback Josh Johnson threw a pair of touchdowns and safety P.J. Locke nabbed an interception.

Meanwhile, Buffalo took care of business at home against the Indianapolis Colts, winning by a score of 27-24. It was an impressive game for the rookies as wide receiver Khalil Skakir logged 92 yards on 5 receptions and Raheem Blackshear reached the end zone twice despite seeing only six carries.

Broncos vs Bills Odds & Spread

All NFL preseason betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: DEN: (+140) | BUF: (-165)
Spread: DEN: +3 (-110) | BUF: -3 (-110)
Total: 39.5 — Over: (-110) | Under: (-110)

The Broncos enter this contest as a slight underdog on the moneyline and the spread. This 1 p.m. ET clash also features the second-lowest total of Saturday's nine-game preseason slate.

Broncos vs Bills Prediction & Pick

There's no denying that the Broncos played well last weekend, but it's concerning that all of their points came in the same quarter (second). They looked sluggish coming back from halftime and leaned on a strong defense to get the victory. The same thing cannot be said about the Bills, though.

Buffalo was in a battle for all four quarters and outscored their opponent by nine points in the fourth quarter for a comeback win. Quarterback Matt Barkley looked crisp, completing 18 of his 24 pass attempts for 224 yards. He'll have another opportunity to dazzle the home crowd on Saturday.

Final Score Prediction: Broncos: 17 | Bills: 24

Broncos vs Bills Betting Trends

- Denver is 1-4 straight up in its last five games against Buffalo.
- The total has hit the under in 15 of Denver's last 20 games.
- Buffalo is 5-0 against the spread (ATS) in its last five games against Denver.
- The total has hit the over in six of Buffalo's last eight games.

Broncos vs Bills Best Bet

All NFL preseason betting lines, odds and prop bets are available on FanDuel Sportsbook.

Betting on preseason winner is certainly risky, but the Bills are too good to pass up here. There's a number of reasons to back head coach Sean McDermott's squad. They have a scorching hot QB in the backfield, a crowd rooting in their favor and a ton of rookies ready to make an impact on offense.

It's worth noting that the Broncos' defensive effort came against Cooper Rush and Ben DiNucci, too. Both of those signal-callers have found little NFL success when compared to Case Keenum and Matt Barkley. Back the Bills to extend their nine-game preseason winning streak to 10 with confidence.

Bet: Buffalo Bills Moneyline (-165)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.