3 Best Prop Bets for 49ers vs Seahawks Thursday Night Football Week 13 (CMC Takes Over on TNF)

Week 15 of the 2022 NFL season kicks off with an NFC West showdown on Thursday Night Football between the San Francisco 49ers and Seattle Seahawks. With both teams featuring potent offenses, this should be an exciting divisional battle.

Here are three of the best prop bets for the 49ers vs Seahawks matchup, courtesy of NFL odds on FanDuel Sportsbook.

49ers vs Seahawks TNF Prop Bets Tonight

1. Christian McCaffrey - Rushing Yards: Over 78.5 (-110)

McCaffrey is coming off a season-high 119 rushing yards last week and is set to lead the 49ers' backfield on Thursday with Deebo Samuel out. That should mean more carries for McCaffrey, who has a golden opportunity to exploit Seattle's 31st-ranked run defense. With rookie QB Brock Purdy still under center for San Francisco, look for Kyle Shanahan to lean heavily on the ground game as well.

2. George Kittle - Receiving Yards: Under 40.5 (-110)

Despite being mostly healthy, Kittle hasn't been as much of a factor in San Francisco's offense this year, as his 45.5 receiving yards per game is his lowest mark since his rookie season. He's been even quieter lately, falling short of 40 yards in five of his last six games, including four games in his last five with fewer than 30 yards. Don't expect that trend to reverse itself with Purdy running the offense, especially if the 49ers end up going run-heavy.

3. Jason Myers - Total Kicking Points: Over 5.5 (-132)

Myers has been one of the most reliable kickers in the NFL all season long, drilling a league-high 96.0% of his field goals (24-for-25) and converting 36 of his 37 extra points. He's also notched at least 6 points in three straight games and 10 of his last 11, making the over on this modest line a good bet for him. The Seahawks could have trouble finding the end zone against a 49ers defense that's giving up the fewest points per game in the NFL, which means Seattle may need to settle for field goals instead. Myers only needs two of those to hit the over on this.

Game odds refresh periodically and are subject to change.