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Virginia vs Syracuse Prediction, Odds & Betting Trends for College Football Game on FanDuel Sportsbook

Larry Rupp
Virginia vs Syracuse prediction, odds and betting trends for NCAA college football game.
Virginia vs Syracuse prediction, odds and betting trends for NCAA college football game. / AP Photos/Adrian Kraus
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Virginia vs Syracuse Week 4 Game Info

2022 NCAA College Football Game
Virginia Cavaliers (2-1, 0-0 ACC) vs. Syracuse Orange (3-0, 1-0 ACC)
Date: Friday, Sept. 23, 2022
Time: 7:00 p.m. ET
Venue: JMA Wireless Dome — Syracuse, NY
Coverage: ESPN

Week 4 of the 2022 NCAA college football season includes an ACC showdown between the Virginia Cavaliers and Syracuse Orange. Virginia snuck by Old Dominion by a score of 16-14 last week to capture its second win of the year. The Cavaliers logged 231 yards on the ground to pace the offense.

Meanwhile, a passing touchdown by quarterback Garrett Schrader with just seconds left on the game clock guided Syracuse to a thrilling 32-29 win over the Purdue Boilermakers on Saturday. It kept the Orange's hopes of an undefeated season alive heading into pivotal ACC conference showdowns.

Virginia vs Syracuse Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: UVA: (+310) | SYR: (-400)
Spread: UVA: +10 (-110) | SYR: -10 (-110)
Total: 54.5 — Over: (-110) | Under: (-110)

Syracuse enters this contest as the clear favorite on the moneyline and the spread. This Friday night clash also features a total of 54.5 points, which is about average compared to this week's college football projected totals.

Virginia vs Syracuse Prediction & Pick

These are two teams heading in completely different directions. Virginia entered the season with high expectations, yet got crushed by Illinois and barely got by Old Dominion at home. On the other side, Syracuse has all the momentum in the world and is putting together its best offensive attack in years.

This battle is going to come down to which defense can cause more issues. Both the Cavaliers and Orange are giving up around 350 yards per game and are allowing less than 20 points per game. With the support of the home crowd behind them, I trust Syracuse will pull away in the second half.

Final Score Prediction: Virginia: 20 | Syracuse: 31

Virginia vs Syracuse Betting Trends

- Virginia is 2-11 straight up in its last 13 away games.
- The total has hit the under in five of Virginia's last six games.
- Syracuse is 7-1 against the spread (ATS) in its last eight home games.
- The total has hit the over in two of Syracuse's three games this season.

Virginia vs Syracuse Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

This spread is high, but that shouldn't scare bettors away from backing the Orange. Virginia is 0-4 against the spread (ATS) in its last four games, while Syracuse is 10-3 ATS in its last 13 games. The Orange are also 7-1 ATS in their last eight home games. They love playing at JMA Wireless Dome.

This Syracuse teams is starting to have a special feel to it. Schrader looks much improved as a passer and running back Sean Tucker is well on his way to ACC accolades as one of the conference's brightest stars. He has already tallied 378 yards from scrimmage and 3 touchdowns this season.

Bet: Syracuse Orange -10 (-110)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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