South Florida vs Cincinnati Prediction, Odds & Betting Trends for College Football Game on FanDuel Sportsbook

South Florida vs Cincinnati Week 6 Game Info

2022 NCAA College Football Game
South Florida (1-4, 0-1 AAC) vs. No. 24 Cincinnati Bearcats (4-1, 1-0 AAC)
Date: Saturday, Oct. 8, 2022
Time: 2:30 p.m. ET
Venue: Nippert Stadium — Cincinnati, OH
Coverage: ESPN

Week 6 of the 2022 NCAA college football season includes an AAC matchup between the Cincinnati Bearcats and South Florida Bulls. It's Homecoming for the Bearcats, who moved back into the AP Top-25 following last week's 31-21 road win at high-flying Tulsa.

South Florida was torched last week at home by East Carolina, 48-28. The Bulls allowed 575 yards of total offense to ECU, including 465 yards through the air.

South Florida vs Cincinnati Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: USF: (+1400) | CIN: (-4000)
Spread: USF: +27.5 (-110) | CIN: -27.5 (-110)
Total: 59.5 — Over: (-108) | Under: (-112)

Cincinnati is a huge home favorite on the spread (-27.5) and moneyline (-4000). The total is 59.5, which is just above an average college football total.

South Florida vs Cincinnati Prediction & Pick

South Florida's defense is last in the AAC with 38 points allowed per game. Meanwhile, Cincinnati's offense tops the AAC in scoring at 40.2 points per game and shouldn't hold anything back with a bye on deck. The Bearcats' offensive line strength against the Bulls' defensive line deficiency is a significant mismatch. South Florida's defense has allowed a whopping 487.4 yards per game, including a league-worst 218 rushing yards per game.

The Bearcats are not running the ball as effectively as expected at 144 yards per game, but Cincinnati QB Ben Bryant has passed for nearly 1,400 yards with 13 TD passes and 8.4 yards per pass. The Cincy's defense just held Tulsa's offense to 285 yards and the Bearcats have won four straight. They should be able to shut down the Bulls' offense and the final score will not be close.

Final Score Prediction: Cincinnati: 49 | USF: 13

South Florida vs Cincinnati Betting Trends

- South Florida is 1-9 straight up (SU) in their last 10 games.
- South Florida is 1-4 against the spread (ATS) in their last 5 games.
- South Florida is 0-14 SU in their last 14 road games.
- South Florida is 7-0 ATS in their last 7 games against Cincinnati.
- Cincinnati is 17-2 SU in their last 19 games.
- Cincinnati is 20-0 SU in their last 20 home games.
- The total has gone Over in 4 of Cincinnati's last 5 games.

South Florida vs Cincinnati Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

South Florida has surprisingly gone 7-0 ATS in the last 7 meetings against Cincinnati, including last year's 45-28 loss as a 23-point underdog. A Bearcats blowout looks like the most likely outcome against the defenseless Bulls.

Bet: Cincinnati -27.5 (-110)