Seahawks vs 49ers Expert Picks & Predictions for Week 2 NFL Game

Seahawks vs 49ers Expert Picks & Predictions for Week 2 NFL Game

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The 2022 NFL season is finally here and the Week 2 schedule is chock full of exciting showdowns. One of the most anticipated matchups of the week is a tilt between two NFC West rivals as the Seattle Seahawks visit the San Francisco 49ers.

Momentum is on the Seahawks' side after spoiling Russell Wilson's homecoming, walking out of Week 1 with the 17-16 victory over the Denver Broncos. The 49ers weren't as fortunate in their season opener, falling short, 19-10, to the Chicago Bears.

The Seahawks have had tremendous success against their rivals lately, winning 17 of the last 20 meetings against the 49ers. Considering how Seattle has also won each of the last four matchups, does San Francisco have what it takes to reverse its fortunes?

Here's what projection models and experts across the industry have to say about the Seahawks vs 49ers Week 2 matchup.

Seahawks vs 49ers Projections

ESPN FPI49ers (72.8%)
numberFire49ers (60.7%)
FiveThirtyEight49ers (69%)
Betting Favorite49ers (-8.5)

Projected Winner: 49ers (4)

Seahawks vs 49ers Expert Picks

ESPN Experts: 49ers (7), Seahawks (3)
Sports Illustrated Experts49ers (5)
CBS Sports ExpertsSeahawks (5), 49ers (2)

Expert Totals: 49ers (14), Seahawks (8)

Even though the Seahawks have had the better of the 49ers, their luck is projected to run out. In addition to all four projections pointing to a San Francisco win, 63.6% of experts also side with the 49ers.

Meanwhile, the Seahawks' best shot at winning comes at 39.3% on numberFire.

Although unfavorable weather could play a factor in the final result, all signs point to the 49ers winning on Sunday.

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.