Rams vs Saints Prediction, Odds & Best Bet for Week 11 (Saints Exploit LA's Injury Woes En Route to Victory)

Rams vs Saints Week 11 Game Info

2022 NFL Regular Season Game
Los Angeles Rams (3-6, 1-2 Away) vs. New Orleans Saints (3-7, 2-4 Home)
Date: Sunday, Nov. 20, 2022
Time: 1 p.m. ET
Venue: Caesars Superdome — New Orleans, LA
Coverage: FOX

Week 11 of the 2022 NFL season includes a showdown between the Los Angeles Rams and New Orleans Saints. The Rams struggled in QB Matthew Stafford's absence last week, generating only 256 total yards in a 27-17 loss to the rival Arizona Cardinals.

The Saints have also struggled to win lately, picking up losses in four of their last five outings — including a 20-10 loss to the Pittsburgh Steelers last week. Andy Dalton had a day to forget under center, going just 17-of-27 in the pocket for 174 yards, one touchdown, two interceptions and a 23.9 QB rating.

Rams vs Saints Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: LAR: (+118) | NO: (-138)
Spread: LAR: +2.5 (-114) | NO: -2.5 (-106)
Total: 39.5 —Over: (-104) | Under: (-118)

Updated (Sunday, Nov. 20, 12:30 p.m. ET): The line has moved in LA's favor. Los Angeles opened the week as a 4-point underdog, but that spread is down to just 2.5 points. The moneyline odds reflect this change. And the over/under moved up one point to 39.5.

The Saints enter this contest as clear favorites on the moneyline and spread on FanDuel Sportsbook's updated odds. This NFC clash also features an over/under of 38.5, which is tied for the lowest of the Week 11 totals. 

Rams vs Saints Prediction & Pick

With Stafford still in concussion protocol, there's a good chance that John Wolford will make his second straight start for the Rams. Even though Los Angeles' offense has looked awful for the majority of the campaign, it looked even worse with Wolford as the signal-caller, generating only 190 passing yards and 66 rushing yards over 12 drives.

Have the Saints looked much better than the Rams lately? Not at all but New Orleans at least has three different QBs that it can turn to. Besides, the Saints' offense also looks more complete in general now that the Rams have placed star wideout Cooper Kupp on the injured reserve.

Without their top offensive duo, there isn't much of a reason to like the Rams. I'm taking the Saints winning a game that likely won't have the most polished football being played.

Final Score Prediction: Saints: 19 | Rams: 14

Rams vs Saints Betting Trends

- The Rams are 2-8-1 against the spread (ATS) in their last 11 games.
- New Orleans is 4-2 ATS in their last six games as the favorite.
- The total has hit the under in five of the Rams' last six road games.
- The total has hit the under in four of New Orleans' last six games against the Rams.

Rams vs Saints Best Bet

The idea of the Rams without Stafford and Kupp is horrifying. I'm uncertain where the offense will come, which has me leaning towards the Saints as far as spread betting is concerned. Furthermore, New Orleans is 4-2 against the spread (ATS) in its last six games as the favorite while Los Angeles is 2-6-1 ATS in 2022.

It won't be the prettiest win due to their own issues, but back the Saints to cover the 4-point spread at home.

Bet: Saints -4 (-110)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.